Erjuan Ning

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A novel long-circulating and pH-responsive dendrimer nanocarrier was prepared for delivering 5-fluorouracil (5-FU) to tumors through the targeting of nanoparticles to the low pH environment of tumors. The nanocarrier, poly(2-(N,N-diethylamino)ethyl methacrylate) with methoxy-poly(ethylene glycol)-poly(amidoamine) (PPD), had a core-shell structure with 4.0 G(More)
The chorionic cells cultured in vitro were treated with the inducing factors of fragile sites. These factors could lead to an unbalance of the dNTP pools and thus induce expression of both common fragile sites and Fra(X). Excess guanosine (250 mg/l) or thymidine (250 mg/l) was added to the culture medium 24 hours before harvest. MEM-FA medium was added 48(More)
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