Erin M Dwyer

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We tested the hypothesis that vasoregulatory mechanisms completely counteract the effects of sudden changes in arterial perfusion pressure on exercising muscle blood flow. Twelve healthy young subjects (7 female, 5 male) lay supine and performed rhythmic isometric handgrip contractions (2 s contraction/ 2 s relaxation 30% maximal voluntary contraction).(More)
The reactive hyperemia test (RHtest) evokes a transient increase in shear stress as a stimulus for endothelial-dependent flow-mediated vasodilation (EDFMD). We developed a noninvasive method to create controlled elevations in brachial artery (BA) shear rate (SR, estimate of shear stress), controlled hyperemia test (CHtest), and assessed the impact of this(More)
In summary, the electrocardiogram is limited in its ability to detect a myocardial infarction. Its sensitivity is compromised seriously by a substantial number of patients (table; see text) with non-Q wave infarction or regression of Q waves. Once a Q wave occurs, the predictive accuracy of those changes, in delineating the location of the infarction, is(More)
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