Recent research into the Guillain-Barré syndromes (GBS) has focused on anti-ganglioside antibodies that correlate with specific clinical phenotypes. Our increasing understanding of the role of antibodies in mediating GBS has naturally focused our attention on complement involvement in the pathological procession. We have studied the axonal and glial… (More)
We report the use of three-dimensional or 3D printed, patient-specific anatomy as a tool to improve informed patient consent and patient understanding in a case of posterior lumbar fixation. Next, we discuss its utility as an educational tool to enhance imaging interpretation by neurosurgery trainees.
The automatic detection and localization of anatomical landmarks has wide application, including intra and inter-patient registration, study location and navigation, and the targeting of specialized algorithms. In this paper, we demonstrate the automatic detection and localization of 127 anatomically defined landmarks distributed throughout the body,… (More)
Multi-parametric MR image registration combines different imaging sequences to enhance visualisation and analysis. However, alignment of the different acquisitions is challenging , due to contrast-dependent anatomical information and abundant artefacts. For two decades, voxel-based registration has been dominated by methods based on mutual information,… (More)
The evolution of medical imaging technologies and computer graphics is leading to dramatic improvements for medical training, diagnosis and treatment, and patient understanding. This paper discusses how volumetric visualization and 3D scanning can be integrated with cadaveric dissection to deliver benefits in the key areas of clinician-patient communication… (More)