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Comprising more than 61,000 servers located across nearly 1,000 networks in 70 countries worldwide, the Akamai platform delivers hundreds of billions of Internet interactions daily, helping thousands of enterprises boost the performance and reliability of their Internet applications. In this paper, we give an overview of the components and capabilities of(More)
—A capsule-based active network transports capsules containing code to be executed on network nodes through which they pass. Active networks facilitate the deployment of new protocols, which can be used without any changes to the underlying network infrastructure. This paper describes the design, implementation, and evaluation of a high-performance active(More)
The Virtual Environment Vehicle Interface (VEVI), developed by the NASA Ames Research Center's Intelligent Mechanisms Group, is a modular operator interface for direct teleoperation and supervisory control of robotic vehicles. Virtual environments enable the efficient display and visual-ization of complex data. This characteristic allows operators to(More)
We have identified a synthetic peptide derived from the secreted portion of HSV type 2 glycoprotein G, denoted gG-2p20, which has proinflammatory properties in vitro. The gG-2p20 peptide, corresponding to aa 190-205 of glycoprotein G-2, was a chemoattractant for both monocytes and neutrophils in a dose-dependent fashion, and also induced the release of(More)
The transition to IPv6 cellular networks creates uncertainty for content providers (CPs) and content delivery networks (CDNs) of whether and how to follow suit. Do CPs that update their CDN contracts to allow IPv6 hosting achieve better, or worse performance in mobile networks? Should CDNs continue to host mobile content over IPv4 networks, or persuade to(More)
The Virtual Environment Vehicle Interface (VEVI) is a software environment developed for the control and visualization of remotely located robotic vehicles. The design and implementation of this interface were driven by experience with several field missions which have defined key areas to be addressed. This paper describes three of these concepts and(More)
We describe here a new animal model that offers the prospect of using conventional adult mice for direct evaluation of the protective potential of new cholera vaccines. Pretreatment of adult mice with oral streptomycin allowed intestinal colonization by streptomycin-resistant Vibrio cholerae strains of either the O1 or the O139 serogroup. Bacteria were(More)
Enterotoxigenic Escherichia coli (ETEC) cause secretory diarrhea in children and travelers to endemic areas. ETEC spreads through the fecal-oral route. After ingestion, ETEC passes through the stomach and duodenum before it colonizes the lower part of the small intestine, exposing bacteria to a wide range of pH and environmental conditions. This study aimed(More)
Migratory populations often stop over for short periods of time at predictable sites along their migration routes. These staging areas can be heavily used and are potentially critical to the survival of the migrants. This paper presents a method for estimating the number of individuals using such an area and their average residence time. The estimator is(More)