Erik David Spoerke

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While titanium has been clinically successful as an orthopedic or dental implant material, performance problems still persist related to implant-bone interfacial strength and mechanical modulus mismatch between titanium and tissue. We describe here the preparation of a titanium foam as a better mechanical match to tissue with surfaces attractive to bone(More)
Fullerenes such as C(60) show promise as functional components in several emerging technologies. For biomedical applications, C(60) has been used in gene- and drug-delivery vectors, as imaging agents, and as photosensitizers in cancer therapy. A major drawback of C(60) for bioapplications is its insolubility in water. To overcome this limitation, we(More)
Bone is one of Nature's most remarkable materials, not only for its mechanical properties but also for its ability to repair fractures and remodel its microstructure in response to stress. At the nanoscale bone is a supramolecular matrix of collagen fibers reinforced by hydroxyapatite crystals with a high degree of order. Emulating elements of the(More)
Porous titanium with elongated and aligned pores, mimicking the anisotropic structure of bone, was created by solid-state expansion of argon trapped in elongated pores between titanium wires. Both elastic moduli and yield strengths are larger in the longitudinal direction (E = 51 GPa, sigma y = 338 MPa) than in the transverse direction (E = 41 GPa, sigma y(More)
Titanium (Ti) and its alloys continue to serve as successful implant materials for skeletal repair because of their physical properties and biocompatibility. This study investigates the influence of organoapatite (OA), grown directly onto an L-shaped Ti mesh, on preosteoblastic cellular colonization. Unseeded mesh samples were placed on subconfluent layers(More)
Nanostructured films and coatings with controlled surface area, porosity, crystalline orientation, grain sizes, and crystal morphologies are desirable for many applications, including microelectronic devices, chemical and biological sensing and diagnosis, energy conversion and storage (photovoltaic cells, batteries and capacitors, and hydrogen-storage(More)
Recently we discovered that under certain conditions new crystal growth (branch) can be induced on specific crystalline planes of the same material. This is a new phenomenon and is in sharp contrast to typical nucleation and growth in which a crystal will simply grow larger in preferred directions depending on the surface energy of the specific crystalline(More)
Microtubules (MTs) are polar protein filaments that participate in critical biological functions ranging from motor protein direction to coordination of chromosome separation during cell division. The effective facilitation of these processes, however, requires careful regulation of the polar orientation and spatial organization of the assembled MTs. We(More)
The nucleation and growth of metal-organic frameworks onto functional surfaces stands to facilitate the utility of these supramolecular crystalline materials across a wide range of applications. Here, we demonstrate the solvothermal nucleation and growth of a pillared paddlewheel porphyrin framework 5 (PPF-5) onto semiconductor surfaces modified with(More)