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Enhanced Direct Major Histocompatibility Complex Class I Self-Antigen Presentation Induced by Chlamydia Infection
ABSTRACT The direct major histocompatibility complex (MHC) class I antigen presentation pathway ensures intracellular peptides are displayed at the cellular surface for recognition of infected orExpand
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Chlamydia spp. development is differentially altered by treatment with the LpxC inhibitor LPC-011
BackgroundChlamydia species are obligate intracellular bacteria that infect a broad range of mammalian hosts. Members of related genera are pathogens of a variety of vertebrate and invertebrateExpand
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Chlamydial infection and the efficiency of MHC class I self-antigen presentation in a lymphoblastoid cell line
The direct MHC class I antigen presentation pathway presents cytosolic proteins for immune surveillance. While this pathway is an attractive target for therapeutics, we must first understand theExpand