Erik Birgersson

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The functional integrity and pathology of the skin is reflected in its electrical impedance spectra. Non-invasive electrical impedance measurements of intact skin are dominated by the high impedic stratum corneum in low frequencies and with increasing frequency gradually comes to be dominated by viable skin. Models of this multi-layered organ can increase(More)
In vitro drug testing requires long-term maintenance of hepatocyte liver specific functions. Hepatocytes cultured at a higher seeding density in a sandwich configuration exhibit an increased level of liver specific functions when compared to low density cultures due to the better cell to cell contacts that promote long term maintenance of polarity and liver(More)
During expiration, the carbon dioxide (CO2) levels inside the dead space of a filtering facepiece respirator (FFR) increase significantly above the ambient concentration. To reduce the CO2 concentration inside the dead space, we attach an active lightweight venting system (AVS) comprising a one-way valve, a blower and a battery in a housing to a FFR. The(More)
A steady-state isothermal model is presented for the electrochemical reduction of CO 2 to CO in a microfluidic flow cell. The full cell model integrates the transport of charge, mass, and momentum with electrochemistry for both the cathode and anode. Polarization curves obtained from experiments conducted at different flow rates with varying applied cell(More)
The importance of in vitro hepatotoxicity testing during early stages of drug development in the pharmaceutical industry demands effective bioreactor models with optimized conditions. While perfusion bioreactors have been proven to enhance mass transfer and liver specific functions over a long period of culture, the flow-induced shear stress has less(More)
This thesis deals with modelling of two types of fuel cells, namely the direct methanol fuel cell (DMFC) and proton exchange membrane fuel cell (PEMFC). One-phase models, comprising conservation of mass, momentum and species, are derived and analysed for the anode of the DMFC and the cathode of the PEMFC. The impact of hydrodynamic, electrochemical and(More)
By reformulation of the fixed charge density and consideration of finite deformation, a previous model simulating the pH-sensitive hydrogels is refined in this paper for extension to simulating the electric-sensitive hydrogels, which is termed the refined multi-effect-coupling electric-stimulus (rMECe) model. The rMECe model is based on the assumptions: (a)(More)
A methodology to determine dielectrical properties of human skin is presented and analyzed. In short, it is based on a mathematical model that considers the local transport of charge in the various layers of the skin, which is coupled with impedance measurements of both stripped and intact skin, an automated code generator, and an optimization algorithm.(More)