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Structural health monitoring (SHM) is an active area of research devoted to systems that can autonomously and proactively assess the structural integrity of bridges, buildings, and aerospace vehicles. Recent technological advances promise the eventual ability to cover a large civil structure with low-cost wireless sensors that can continuously monitor a(More)
Corticotropin-releasing factor (CRF) is a neuropeptide found throughout the central nervous system that has a proposed role in modulating emotional and behavioral states, including stress and anxiety. The amygdala, which is important in the control of emotional and autonomic responses to stress, contains CRF nerve terminals, CRF cell bodies, and CRF(More)
Exposure of pregnant rats to stress results in offspring that exhibit abnormally fearful behavior and have elevated neuroendocrine responses to novelty and aversive stimuli. This study examined the effects of prenatal stress on plasma corticosterone, adrenal weight, defensive withdrawal behavior, and the density of receptors for corticotropin releasing(More)
BACKGROUND Exposure to the nerve agent soman (GD) causes neuronal cell death and impaired behavioral function dependent on the induction of status epilepticus (SE). Little is known about the maturation of this pathological process, though neuroinflammation and infiltration of neutrophils are prominent features. The purpose of this study is to quantify the(More)
In this study, we examined the expression and cellular localization of survivin and proliferating cell nuclear antigen (PCNA) after controlled cortical impact traumatic brain injury (TBI) in rats. There was a remarkable and sustained induction of survivin mRNA and protein in the ipsilateral cortex and hippocampus of rats after TBI, peaking at five days post(More)
— Structural health monitoring (SHM) is an important application area for wireless sensor networks. Recent work has examined the design of wireless sensor networks for structural data acquisition systems. The eventual goal of structural monitoring , however, is autonomous detection and localization of structural damage. Developing practical damage detection(More)
The voltage and time-dependence of the tetrodotoxin sensitive, fast sodium current in cardiac muscle is described with the Hodgkin-Huxley formalism using two microelectrode, voltage-clamp data obtained by Ebihara et al. (1980, J. Gen. Physiol., 75:437) from small spherical clusters of tissue-cultured 11-d-old embryonic heart cells. The data chosen from that(More)
The electrochemical properties of a widely accepted six-step reaction scheme for the Na+, K+-ATPase have been studied by computer simulation. Rate coefficients were chosen to fit the nonvectorial biochemical data for the isolated enzyme and a current-voltage (I-V) relation consistent with physiological observations was obtained with voltage dependence(More)
BACKGROUND Neuroinflammation occurs following brain injury, including soman (GD) induced status epilepticus (SE), and may contribute to loss of neural tissue and declined behavioral function. However, little is known about this important pathological process following GD exposure. Limited transcriptional information on a small number of brain-expressed(More)
1 This paper describes an ongoing project investigating embedded networked sensing for structural health monitoring applications. The vision is of many low-power sensor " motes " embedded throughout the structure with a smaller number of nodes that can provide local excitation. The challenge is to develop both the networking algorithms to reliably(More)