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A BSTRACT : Stay cables, such as are used in cable-stayed bridges, are prone to vibration due to their low inherent damping characteristics. Transversely-attached passive viscous dampers have been implemented in many bridges to dampen such vibration. Several studies have investigated optimal passive linear viscous dampers; however, even the optimal passive(More)
Structural health monitoring (SHM) is an active area of research devoted to systems that can autonomously and proactively assess the structural integrity of bridges, buildings, and aerospace vehicles. Recent technological advances promise the eventual ability to cover a large civil structure with low-cost wireless sensors that can continuously monitor a(More)
1 This paper describes an ongoing project investigating embedded networked sensing for structural health monitoring applications. The vision is of many low-power sensor " motes " embedded throughout the structure with a smaller number of nodes that can provide local excitation. The challenge is to develop both the networking algorithms to reliably(More)
BACKGROUND Exposure to the nerve agent soman (GD) causes neuronal cell death and impaired behavioral function dependent on the induction of status epilepticus (SE). Little is known about the maturation of this pathological process, though neuroinflammation and infiltration of neutrophils are prominent features. The purpose of this study is to quantify the(More)
BACKGROUND Neuroinflammation occurs following brain injury, including soman (GD) induced status epilepticus (SE), and may contribute to loss of neural tissue and declined behavioral function. However, little is known about this important pathological process following GD exposure. Limited transcriptional information on a small number of brain-expressed(More)
Accumulation of non-erythroid aII-spectrin and calpain-cleaved aII-spectrin breakdown products in cerebrospinal ¯uid after traumatic brain injury in rats Abstract Although a number of increased CSF proteins have been correlated with brain damage and outcome after traumatic brain injury (TBI), a major limitation of currently tested biomarkers is a lack of(More)
In this study, we examined the expression and cellular localization of survivin and proliferating cell nuclear antigen (PCNA) after controlled cortical impact traumatic brain injury (TBI) in rats. There was a remarkable and sustained induction of survivin mRNA and protein in the ipsilateral cortex and hippocampus of rats after TBI, peaking at five days post(More)
With the advent of miniaturized sensing technology, it has become possible to envision smart structures containing millions of sensors embedded in concrete for autonomously detecting and locating incipient damage. Where are we today in our march towards this vision of autonomous structural health monitoring (SHM) using networked embedded sensing? In this(More)
Survivin attenuates apoptosis by inhibiting cleavage of some cell proteins by activated caspase-3. We recently discovered strong up-regulation of survivin, primarily in astrocytes and a sub-set of neurons, after traumatic brain injury (TBI) in rats. In this study we characterized co-expression of survivin with activated caspase-3 and downstream DNA(More)
The nite element method has been previously applied to the solution of the Fokker-Planck equation for second order systems under additive white noise exci-tation. Animation of these solutions has provided insights into previously unstudied nonstationary behavior of the transition probability density functions of these systems. This work has now been(More)