Eric Walter Pefura-Yone

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BACKGROUND We investigated the determinants of sputum culture non-conversion following intensive phase of treatment, and assessed the effects on the outcome among patients treated for a first episode of smear positive tuberculosis (TB). METHODS This was a prospective cohort study spanning October 2009 to May 2012, among patients treated for a first(More)
OBJECTIVES Mortality has declined in people with HIV infection, subsequent to the improved access to antiretroviral therapy (ART). We assessed the incidence and determinants of mortality among patients with HIV-1 infection who were started on ART in a referral treatment centre for HIV infection in Yaounde, Cameroon. DESIGN Cohort study with baseline(More)
OBJECTIVES The aim of this study was to assess the prevalence and determinants of post-tuberculosis chronic respiratory signs, as well as the clinical impact of a low forced expiratory flow between 25% and 75% (FEF25-75%) in a group of individuals previously treated successfully for pulmonary tuberculosis. DESIGN This was a cross-sectional study involving(More)
OBJECTIVES Sensitisation of asthmatic patients to mites in sub-Saharan Africa has been less described. The aim of this study was to assess the prevalence and determinants of sensitisation to mites in asthmatic adolescents and adults in Yaounde, Cameroon. DESIGN This was a cross-sectional study. Logistic regression models were employed to investigate the(More)
BACKGROUND German cockroach or Blattella germanica is commonly found in homes across the inter-tropical region. The contribution of sensitisation to Blattella germanica in people with asthma in sub-Saharan Africa has not received attention. The aim of this study was to assess the prevalence and investigate the predicting factors of sensitisation to(More)
BACKGROUND Population-based estimates of asthma and allergic rhinitis in sub-Saharan African adults are lacking. We assessed the prevalence and determinants of asthma and allergic rhinitis in urban adult Cameroonians. METHODS A community-based survey was conducted from December 2013 to April 2014 among adults aged 19 years and above (N = 2,304, 57.3%(More)
BACKGROUND Restrictive spirometric pattern is a risk factor for all-cause and cause-specific mortality. OBJECTIVE We assessed the prevalence of restrictive pattern and investigated its determinants in a major sub-Saharan Africa city. METHODS Participants were adults (≥ 19 years) who took part in a population-based survey in Yaounde (Cameroon) between(More)
BACKGROUND Death under care is a major challenge for tuberculosis (TB) treatment programs. We derived and validated a simple score to predict mortality during tuberculosis treatment in high endemicity areas. METHODS We used data for patients aged ≥15 years, diagnosed and treated for tuberculosis at the Yaounde Jamot Hospital between January 2012 and(More)
Obstructive lung disease (OLD), a major global public health problem, has been less investigated in African countries. We assessed the prevalence and determinants of OLD in Yaounde (the capital city of Cameroon), using internationally agreed definitions. Participants were adults (age >19 years) screened during a community-based survey between December 2013(More)
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