Eric Walter Pefura-Yone

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BACKGROUND We investigated the determinants of sputum culture non-conversion following intensive phase of treatment, and assessed the effects on the outcome among patients treated for a first episode of smear positive tuberculosis (TB). METHODS This was a prospective cohort study spanning October 2009 to May 2012, among patients treated for a first(More)
PURPOSE To assess the prevalence and determinants of non-adherence to antiretroviral therapy (ART) as well as the concordance of two screening criteria in a major center for human immunodeficiency virus (HIV) treatment in Yaounde, Cameroon. METHODS In 2011, we conducted a cross-sectional study involving a random sample of 889 adults (age > 18 years, 67.9%(More)
OBJECTIVES Mortality has declined in people with HIV infection, subsequent to the improved access to antiretroviral therapy (ART). We assessed the incidence and determinants of mortality among patients with HIV-1 infection who were started on ART in a referral treatment centre for HIV infection in Yaounde, Cameroon. DESIGN Cohort study with baseline(More)
OBJECTIVES Sensitisation of asthmatic patients to mites in sub-Saharan Africa has been less described. The aim of this study was to assess the prevalence and determinants of sensitisation to mites in asthmatic adolescents and adults in Yaounde, Cameroon. DESIGN This was a cross-sectional study. Logistic regression models were employed to investigate the(More)
BACKGROUND German cockroach or Blattella germanica is commonly found in homes across the inter-tropical region. The contribution of sensitisation to Blattella germanica in people with asthma in sub-Saharan Africa has not received attention. The aim of this study was to assess the prevalence and investigate the predicting factors of sensitisation to(More)
OBJECTIVES The distribution and impact of various aeroallergens on asthma occurrence vary across regions. We investigated the association between sensitisation to perennial aeroallergens and asthma risk in children and adolescents in Yaounde, Cameroon. METHODS This was a case-control study involving children and adolescents with asthma (cases) vs.(More)
OBJECTIVES The aim of this study was to assess the prevalence and determinants of post-tuberculosis chronic respiratory signs, as well as the clinical impact of a low forced expiratory flow between 25% and 75% (FEF25-75%) in a group of individuals previously treated successfully for pulmonary tuberculosis. DESIGN This was a cross-sectional study involving(More)
BACKGROUND Little is known on the association between HIV infection and chronic obstructive pulmonary disease (COPD) in sub-Saharan Africa. We assessed the prevalence and investigated the determinants of COPD according to HIV status in a reference centre for HIV and tuberculosis (TB) management in Cameroon. METHODS This case-control study involved 461(More)
BACKGROUND Population-based estimates of asthma and allergic rhinitis in sub-Saharan African adults are lacking. We assessed the prevalence and determinants of asthma and allergic rhinitis in urban adult Cameroonians. METHODS A community-based survey was conducted from December 2013 to April 2014 among adults aged 19 years and above (N = 2,304, 57.3%(More)
INTRODUCTION To derive and validate against the Ralph et al. score, a simplified chest X-ray (CXR) score (SCS) for predicting the outcome of smear-positive pulmonary tuberculosis (SPPTB) among patients with high prevalence of human immunodeficiency virus (HIV) infection. METHODS CXR for 636 SPPTB patients (377 men, median age 31 years) from the Yaounde(More)