Eric T Lagally

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A monolithic integrated DNA analysis system comprised of microfluidic valves and vents, PCR amplification chambers, and capillary electrophoretic separation channels has been microfabricated in a glass sandwich structure. Valves and hydrophobic vents provide controlled and sensorless sample loading into 280 nl PCR chambers; the low volume reactor and the(More)
We have directly integrated a continuous-flow, electrokinetic method of bacterial cell concentration with room temperature, sequence-specific genetic detection. The system we have developed traps cells from a continuous-flow sample stream via dielectrophoresis, providing a 160-fold increase in cell concentration. PDMS microvalves then define a 100 nL volume(More)
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