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Image classification is an important task in computer vision. However, how to assign suitable labels to images is a subjective matter, especially when some images can be categorized into multiple classes simultaneously. Multilabel image classification focuses on the problem that each image can have one or multiple labels. It is known that manually labelling(More)
Abstract Rationale. Marijuana is known to have psychotropic effects in humans. In this study, we used rat models of sensorimotor gating, hyperactivity and stereotypy to explore whether CB1 receptor stimulation or blockade induces behavioral changes consistent with psychotomimetic or antipsychotic agents, respectively. Objectives. We determined whether (a)(More)
In this paper, we present a novel approach, called the “one-circle” algorithm, for measuring the eye gaze using a monocular image that zooms in on only one eye of a person. Observing that the iris contour is a circle, we estimate the normal direction of this iris circle, considered as the eye gaze, from its elliptical image. From basic projective geometry,(More)
The use of SVM (Support Vector Machine) as component classifier in AdaBoost may seem like going against the grain of the Boosting principle since SVM is not an easy classifier to train. Moreover, Wickramaratna et al. [2001. Performance degradation in boosting. In: Proceedings of the Second International Workshop on Multiple Classifier Systems, pp. 11–21](More)
A deformable-model based approach is presented in this paper for robust detection of optic disk and cup boundaries. Earlier work on disk boundary detection up to now could not effectively solve the problem of vessel occlusion. The method proposed here improves and extends the original snake, which is essentially a deforming-only technique, in two aspects:(More)
There are two components to the human visual line-of-sight: pose of human head and the orientation of the eye within their sockets. We have investigated these two aspects but will concentrate on eye gaze estimation. We present a novel approach called the "one-circle" algorithm for measuring the eye gaze using a monocular image that zooms in on only one eye(More)
Antagonists at serotonin type 6 (5-HT(6)) receptors show activity in models of learning and memory. Although the underlying mechanism(s) are not well understood, these effects may involve an increase in acetylcholine (ACh) levels. The present study sought to characterize the cognitive-enhancing effects of the 5-HT(6) antagonist Ro4368554(More)
An animal model of Leber hereditary optic neuropathy (LHON) was produced by introducing the human optic atrophy mtDNA ND6 P25L mutation into the mouse. Mice with this mutation exhibited reduction in retinal function by elecroretinogram (ERG), age-related decline in central smaller caliber optic nerve fibers with sparing of larger peripheral fibers, neuronal(More)