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Polycystic ovaries are usually manifest on an ultrasound study as symmetrically enlarged ovaries containing numerous tiny cysts. The cysts are difficult to detect with conventional contact B-scanners but are readily detected with high-resolution, real-time sector scanners. The cysts range in diameter form 2 to 6 mm and may be arranged in the periphery of an(More)
OBJECTIVE The purpose of this study was to describe the normal sonographic appearance and measurement of normal major cranial sutures in neonates and infants. SUBJECTS AND METHODS High-resolution sonograms of sagittal, coronal, and lambdoid sutures were obtained for two autopsy specimens and correlated with histologic sections obtained at identical(More)
The purpose of this study was to evaluate the usefulness of real-time extended field-of view sonography in clinical practice (i.e., the frequency of use in various body systems, the frequency of use by different sonographers, and the benefits and drawbacks in comparison to conventional real-time sonography). The use of extended field-of-view sonography was(More)
High resolution, real-time ultrasound scans were obtained through the anterior fontanelle to examine the intracranial anatomy of 100 neonates. Of 43 patients with abnormalities, 26 had intracranial hemorrhage (subependymal, intraventricular, or cerebral). Of the 51 patients also studied by CT, the sensitivity of ultrasound in detecting hemorrhage was 96%(More)
PURPOSE We have observed cavitation of lesions in clinical trials of an angiogenesis inhibitor combined with chemotherapy for non-small-cell lung cancer (NSCLC). We hypothesized that cavitation might alter response assessment in such clinical trials. PATIENTS AND METHODS We performed a retrospective radiologic review of patients with NSCLC enrolled onto(More)
PURPOSE To evaluate the safety and efficacy of oral everolimus, a mammalian target of rapamycin (mTOR) inhibitor, in two different schedules in minimally pretreated patients with metastatic breast cancer and to explore for possible biologic correlates of response. PATIENTS AND METHODS Patients who received no or one prior chemotherapy regimen for(More)
PURPOSE We investigated the feasibility of using real-time sonography to measure muscle thickness. Clinically, this technique would be used to measure the thickness of human muscles in which intramuscular microstimulators have been implanted to treat or prevent disuse atrophy. METHODS Porcine muscles were implanted with microstimulators and imaged with(More)
Sonograms of the brain were obtained in six neonates with congenital intracranial abnormalities. Two of the six abnormalities were echogenic: a lipoma of the corpus callosum and calcific foci associated with toxoplasmosis. Four were anechoic (fluid) lesions including dilated ventricles in two patients, an aneurysm of the vein of Galen, and a Dandy-Walker(More)
Ninety-eight newborn infants, less than 34 weeks at birth, were studied to examine the relationship between newborn hypotension and hypoxemia and brain damage. Heart rate, blood pressure and oxygen tension were recorded continuously during the 96 h following delivery. Outcome measures included neuropathology in children who died, and motor and cognitive(More)