Eric M. Vigoren

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Organophosphate (OP) pesticides are commonly used in the United States, and farmworkers are at risk for chronic exposure. Using a sample of 218 farmworkers in 24 communities and labor camps in eastern Washington State, we examined the association between agricultural crop and OP pesticide metabolite concentrations in urine samples of adult farmworkers and(More)
BACKGROUND Exposure to organophosphate (OP) pesticides is an occupational hazard for farmworkers and affects their children through the take-home pathway. OBJECTIVES We examined the effectiveness of a randomized community intervention to reduce pesticide exposure among farmworkers and their children. METHODS We conducted a baseline survey of a(More)
BACKGROUND Bisphenol A (BPA) and triclosan (TCS) are two nonpersistent chemicals that have been frequently measured in spot urine samples from the general population but less so in pregnant women; however, data are limited on the free (bioactive) and conjugated forms of these phenols. OBJECTIVES The Maternal-Infant Research on Environmental Chemicals(More)
OBJECTIVES Residential proximity to pesticide-treated farmland is an important pesticide exposure pathway. METHODS In-person interviews and biological samples were collected from 100 farmworker and 100 non-farmworker adults and children living in Eastern Washington State. We examined the relationship of residential proximity to farmland to urinary(More)
BACKGROUND Few studies have examined the relationship between reported health symptoms and exposure to organophosphate (OP) pesticides. METHODS Fisher's exact test was used to assess the relationship between self-reported health symptoms and indicators of exposure to OP pesticides in 211 farmworkers in Eastern Washington. RESULTS The health symptoms(More)
Organophosphate pesticides are commonly used in the United States, and farmworkers are at risk for chronic exposure. Using data from a community randomized trial to interrupt the take-home pathway of pesticide exposure, we examined the association between floor surface type (smooth floor, thin carpet, and thick carpet) and rooms in which dust samples were(More)
OBJECTIVE To assess associations of protective workplace and home practices with pesticide exposure levels. METHODS Using data from orchard workers in the Yakima Valley, Washington, we examined associations of workplace and home protective practices with (1) urinary metabolite concentrations of dimethylthiophosphate (DMTP) in adults and children aged 2 to(More)
OBJECTIVE The objective of this study was to investigate the molecular nature, spectrum of activity and mechanism(s) of action of those human parotid basic proline-rich proteins that exhibit anti-HIV-I activity. DESIGN Fractions containing the basic proline-rich proteins were obtained from human parotid saliva of presumed HIV-I non-infected human subjects(More)
This study characterized the within- and between-child variability in dimethylthiophosphate (DMTP) levels in the urine of 44 children living in an agricultural community in central Washington State in December 1997 and 1999. The goal of this analysis was to investigate these variability components during periods when organophosphate pesticides were and were(More)
OBJECTIVE We examined the effectiveness of a community randomized intervention among farmworkers who did and did not work in pome fruit (apples and pears). METHODS Urine samples were collected from two cross-sectional groups of farmworkers and analyzed for the presence of dimethylthiophosphate. RESULTS There was no significant time by crop interaction(More)