Eric L. Miller

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Multiple Hypothesis Video Segmentation (MHVS) is a method for the unsupervised photometric segmentation of video sequences. MHVS segments arbitrarily long video streams by considering only a few frames at a time, and handles the automatic creation, continuation and termination of labels with no user initialization or supervision. The process begins by(More)
Evolution by natural selection is fundamentally shaped by the fitness landscapes in which it occurs. Yet fitness landscapes are vast and complex, and thus we know relatively little about the long-range constraints they impose on evolutionary dynamics. Here, we exhaustively survey the structural landscapes of RNA molecules of lengths 12 to 18 nucleotides,(More)
Automated sample preparation and electron microscopy enables acquisition of very large image data sets. These technical advances are of special importance to the field of neuroanatomy, as 3D reconstructions of neuronal processes at the nm scale can provide new insight into the fine grained structure of the brain. Segmentation of large-scale electron(More)
We address the problem of automatic 3D segmentation of a stack of electron microscopy sections of brain tissue. Unlike previous efforts, where the reconstruction is usually done on a section-to-section basis, or by the agglomerative clustering of 2D segments, we leverage information from the entire volume to obtain a globally optimal 3D segmentation. To do(More)
In this paper, we present an adaptive two-pass rank order filter to remove impulse noise in highly corrupted images. When the noise ratio is high, rank order filters, such as the median filter for example, can produce unsatisfactory results. Better results can be obtained by applying the filter twice, which we call two-pass filtering. To further improve the(More)
To assess the concern over declining base cation levels in forest soils caused by acid deposition, input-output budgets (1990s average) for sulphate (SO(4)), inorganic nitrogen (NO(3)-N; NH(4)-N), calcium (Ca), magnesium (Mg) and potassium (K) were synthesised for 21 forested catchments from 17 regions in Canada, the United States and Europe. Trend analysis(More)
In this paper, we consider a wavelet based edge-preserving regularization scheme for use in linear image restoration problems. Our efforts build on a collection of mathematical results indicating that wavelets are especially useful for representing functions that contain discontinuities (i.e., edges in two dimensions or jumps in one dimension). We interpret(More)
Medical image processing in general and computerized tomography (CT) in particular can benefit greatly from hardware acceleration. This application domain is marked by computationally intensive algorithms requiring the rapid processing of large amounts of data. To date, reconfigurable hardware has not been applied to this important area. For efficient(More)
The problem of characterizing the structure of an object buried in an inhomogeneous halfspace of unknown composition is considered. We develop a non-linear inverse scattering algorithm based on a low dimensional parameterization of the unknown object and the background. In particular, we use low order polynomials to represent the contrast in the real and(More)
The development of energy selective, photon counting X-ray detectors allows for a wide range of new possibilities in the area of computed tomographic image formation. Under the assumption of perfect energy resolution, here we propose a tensor-based iterative algorithm that simultaneously reconstructs the X-ray attenuation distribution for each energy. We(More)