Eric Hassall

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During the last decade, clinical practice saw a rapid increase of patients with esophageal eosinophilia who were thought to have gastroesophageal reflux disease (GERD) but who did not respond to medical and/or surgical GERD management. Subsequent studies demonstrated that these patients had a "new" disease termed eosinophilic esophagitis (EE). As(More)
OBJECTIVES To develop an international consensus on the definition of gastroesophageal reflux disease (GERD) in the pediatric population. METHODS Using the Delphi process, a set of statements was developed and voted on by an international panel of eight pediatric gastroenterologists. Statements were based on systematic literature searches using Medline,(More)
OBJECTIVE To develop a North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition (NASPGHAN) and European Society for Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) international consensus on the diagnosis and management of gastroesophageal reflux and gastroesophageal reflux disease in the pediatric population. (More)
Helicobacter pylori(H. pylori)는 만성 위염과 소화성 궤양 등의 원인균으로 잘 알려져 있으며 위암과 mucosa associated lymphoid tissue(MALT)와의 관련성도 체계적으로 밝혀져 있 다. 개발도상국에서 H. pylori는 어려서부터 감염되게 되는데 대 부분의 경우 10세 이전에 감염이 시작된다 1) . 한번 감염되면 수 십 년 지속되는 것이 보통이며 자연 박멸률은 극히 낮다 2) . 한국 인에서의 H. pylori 감염의 혈청학적 역학 연구결과에서 보면, 5 세 미만에 1.1%, 5-10세 사이에 12.8%, 10-15세 사이에 20.4% 인 양성률이 20대에 들어서면 66.7%로 급격히(More)
As an alternative to surgical splenectomy, partial splenic embolization was performed in seven children for hypersplenism manifested by splenomegaly, thrombocytopenia, leukopenia, and erythrocyte hemolysis. Within a few days, platelet and leukocyte counts rose significantly in all patients and were maintained in six of seven patients during a follow-up(More)
OBJECTIVE To characterize those pediatric patients who receive long-term proton pump inhibitors (PPIs) and to determine the safety of long-term use of PPIs in this population. STUDY DESIGN Patient databases were screened for long-term PPI use, defined as more than 9 months of continuous prescription, between 1989 and 2004. RESULTS The median duration of(More)
Gastroesophageal reflux is a physiological phenomenon, occurring with different severity and duration in different individuals. Reflux occurs when this normal event results in the occurrence of symptoms/signs or complications. The pathophysiology of gastroesophageal reflux is complex and diverse, since it is influenced by factors that are genetic,(More)
Antireflux surgery has been a mainstay of treatment for gastro-oesophageal reflux disease in children for some 40 years. In recent years, enthusiasm for antireflux surgery seems only to have increased, despite its often poor outcome, and the availability of highly effective medical therapy in the form of proton pump inhibitors (PPIs). Reports show that many(More)
As an update to previously published recommendations for the management of Helicobacter pylori infection, an evidence-based appraisal of 14 topics was undertaken in a consensus conference sponsored by the Canadian Helicobacter Study Group. The goal was to update guidelines based on the best available evidence using an established and uniform methodology to(More)