Eric Garcia

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Human resting B lymphocytes enter a state of sustained proliferation when incubated with both mouse fibroblastic L cells stably expressing FcyRII/CDw32 and anti-CD40 antibodies. We have explored the effects of 11 recombinant human cytokines (CKs) on induced cell proliferation and immunoglobulin (Ig) production. Interleukin 4 (IL4) was the only CK able to(More)
Human CD4(+)CD25(+) regulatory T cells (Treg) play an essential role in the prevention of autoimmune diseases. However, the mechanisms of immune suppression and the spectrum of cells they target in vivo remain incompletely defined. In particular, although Treg directly suppress conventional T cells in vitro, they have been shown to inhibit the Ag-presenting(More)
— Pretouch sensing is longer range than contact, but shorter range than vision. Our hypothesis is that closed loop feedback based on short range but non-contact measurements can improve the reliability of manipulation. Such feedback may be particularly useful in mobile manipulation and personal robotics: mobility increases the robot's position uncertainty,(More)
The tumour microenvironment is shaped by the interaction of tumour cells with a variety of " non " malignant cellular and acellular components. It is the secretion of cytokines, chemokines, metabolites and other mediators in the tumour stroma that shapes the natural evolution of cancer. Whereas the tumour strives to promote an immu-nosuppressive environment(More)
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