Eric DesRosiers

Learn More
The purpose of this study is to provide better understanding of the mechanical response of the lumbodorsal fascia to dynamic and static traction loadings. Since the fascia shows a viscoelastic behaviour, tests in which time is a variable were used, namely hysteresis and stress relaxation. Load-strain and load-time curves obtained from the hysteresis and(More)
The suitability of chitosan-based hydrogels as scaffolds for the encapsulation of intervertebral disc (IVD) cells and the accumulation of a functional extracellular matrix mimicking that of the nucleus pulposus (NP) was investigated. The specific hypothesis under study was that the cationic chitosan would form an ideal environment in which large quantities(More)
A system has been developed to study in vitro the effects of mechanical stimulation on the biomechanical properties of ligaments. The apparatus is based on a ball screw driven by a microcomputer-controlled stepper motor capable of generating 100 Newtons of traction, the resulting force in the tissue is monitored in real-time acquisition by a load cell. It(More)
We investigated the effects of growth factors on the proliferation and matrix synthesis of anterior cruciate ligament fibroblasts. Fibroblasts from the anterior cruciate ligaments of dogs were transferred at the second passage in a defined medium. Epidermal growth factor, platelet-derived growth factor-AB, transforming growth factor-beta 1, insulin-like(More)
A natural poly(hydroxybutyrate-co-9% hydroxyvalerate) copolyester was processed into a three-dimensional porous foam structure by salt leaching/solvent casting with previously sieved sodium chloride salts. Laboratory-built P(HB-9% HV) foams and commercial collagen sponges were cut into small rectangular specimens, sterilized, and prewetted using ethanol,(More)
Mechanical stimulation, as provided by physiotherapy or controlled motion is essentially the only factor able to improve anterior cruciate ligament (ACL) healing. We investigate the cellular effects of such stimulus. Two types of stimulations are applied on canine ACL fibroblasts: repetitive stretch of an elastomeric adhesion substrate and a laminar flow of(More)
Wounded ACL heal very poorly. Following ligament rupture, the initial scar tissue is highly unorganized and is mechanically and biochemically very different from the normal tissue. As fibroblasts play the main part in ligament healing and remodelling process, we try to construct a model of fibroblast's response to various environmental conditions. This type(More)
The equiatomic Nickel-Titanium (NiTi) alloy has exceptional mechanical properties such as shape memory and superelasticity. It already has applications in orthodontics and is a promising orthopaedic biomaterial. Cytocompatibility studies must therefore be undertaken. The objective of this study is to determine the biological response that NiTi elicits(More)
With this study, we identified the maximal level of deformation applicable to medial collateral rabbit ligaments in vitro. According to scanning electron microscopy photographs of ligaments fixed at different elongation level 0% (n = 5), 5% (n = 4), 6% (n = 5), 8% (n = 5), 10% (n = 7), 15% (n = 4) and 20% (n = 4), we concluded that a 6% deformation would be(More)
  • 1