Eric David Eisner

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OBJECTIVE To demonstrate posttraumatic chondrocyte apoptosis in the murine xiphoid after a crush-type injury and to ultimately determine the pathway (i.e., intrinsic or extrinsic) by which chondrocytes undergo apoptosis in response to mechanical injury. DESIGN The xiphoids of adult female wild-type mice were injured with the use of a modified Kelly clamp.(More)
The author hereby grants to M.I.T. permission to reproduce and to distribute publicly paper and electronic copies of this thesis document in whole and in part in any medium now known or hereafter created. ABSTRACT To more accurately predict which genes from different species have the same function (orthologs), I extend the network-alignment algorithm(More)
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