Eric Bell

Learn More
CD4(+) T (helper) cells migrate in huge numbers through lymphoid organs. However, little is known about traffic routes and kinetics of CD4(+) T-cell subsets within different organ compartments. Such information is important because there are indications that CD4(+) T cells may influence the function of microenvironments depending on their developmental(More)
Mesenchymal stem cells (MSCs) are multi-potent cells that can differentiate into osteoblasts, adipocytes, chondrocytes and myocytes. This potential declines with aging. We investigated whether the sirtuin SIRT1 had a function in MSCs by creating MSC specific SIRT1 knock-out (MSCKO) mice. Aged MSCKO mice (2.2 years old) showed defects in tissues derived from(More)
We investigate the mass-to-light ratios of stellar populations as predicted by stellar population synthesis codes and compare those to dynamical/gravitational measurements. In Bell & de Jong (2001) we showed that population synthesis models predict a tight relation between the color and mass-to-light ratio of a stellar population. The normalization of this(More)
  • Martín Rama, Pat Alailima, Eric Bell, Amit Dar, Rapti Goonesekere, Chandra Rodrigo +1 other
  • 1999
The high unemployment rate of Sri Lanka has been attributed to skills mismatch, to queuing for public sector jobs, and to stringent job security regulations. However, the empirical evidence supporting these explanations is weak. This paper takes a fresh look at the unemployment problem using individual records from the 1995 Labor Force Survey and time(More)
The cellular basis of immunological memory remains a controversial area with respect to the identity of memory T cells and the role of persisting antigen. CD4 T cells are phenotypically divided by the expression of high and low molecular weight isoforms of CD45, surface markers that are frequently used to identify "naive" (CD45Rhigh) and "memory" (CD45Rlow)(More)
Experimental studies of the T cell requirement for rejection of class I major histocompatibility complex (MHC)-disparate grafts have generated controversy over both the autonomy of CD8+ T cells and the mechanism whereby CD4+ T cells are able to independently mediate rejection. In this study of rejection of RT1Aa class I MHC-disparate rat cardiac and skin(More)