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- Publications
- Influence
Ketopiperazine-based renin inhibitors: optimization of the "C" ring.
- D. Holsworth, C. Cai, +18 authors S. Maiti
- Chemistry, Medicine
- Bioorganic & medicinal chemistry letters
- 13 June 2006
A systematic investigation of the S3 sub-pocket activity requirements was conducted. It was observed that linear and sterically small side chain substituents are preferred in the S3 sub-pocket for… Expand
Evaluation of synthetic coumarins for antiausterity cytotoxicity against pancreatic cancers.
- C. Farley, D. F. Dibwe, Jun-ya Ueda, Eric A. Hall, S. Awale, J. Magolan
- Chemistry, Medicine
- Bioorganic & medicinal chemistry letters
- 1 March 2016
A series of functionalized coumarins were synthesized and evaluated for their capacity to inhibit the resistance to starvation of pancreatic cancer cells. This form of cytotoxicity, termed… Expand
Ketopiperazine-based renin inhibitors: optimization of the
- D. Holsworth, C. Cai, +18 authors S. Maiti
- Chemistry
- 2006