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Inhalation of Stachybotrys chartarum Evokes Pulmonary Arterial Remodeling in Mice, Attenuated by Rho-Kinase Inhibitor
Stachybotrys chartarum, a ubiquitous fungus in our environment, has been suspected of causing respiratory symptoms in humans, such as acute infant pulmonary hemorrhage and asthma. We previouslyExpand
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Secondary metabolite profiles and antifungal drug susceptibility of Aspergillus fumigatus and closely related species, Aspergillus lentulus, Aspergillus udagawae, and Aspergillus viridinutans.
The incidence of Aspergillus infection has been increasing in the past few years. Also, new Aspergillus fumigatus-related species, namely Aspergillus lentulus, Aspergillus udagawae, and AspergillusExpand
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Inhalation of Stachybotrys chartarum causes pulmonary arterial hypertension in mice
Inhalation of Stachybotrys chartarum, a ubiquitous fungus in our living environment, has been suspected as a cause of acute idiopathic pulmonary haemorrhage in infants, but its relation to humanExpand
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The Pathogenicity of Stachybotrys chartarum.
Stachybotrys chartarum is a dematiaceous fungus that is ubiquitous in our living environment. This fungus has long been regarded as non-pathogenic and its inhalation effect on humans has beenExpand
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Cerebral Toxoplasmosis. Pathogenesis, Host Resistance and Behavioural Consequences.
Abstract Following infection with Toxoplasma gondii, tachyzoites proliferate within a variety of nucleated cells in various organs during the acute stage of infection. Interferon-gammaExpand
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Cytotoxic Substances from Aspergillus fumigatus in Oxygenated or Poorly Oxygenated Environment
Aspergillus fumigatus often causes serious health problems. The airway of the human body, the most common initial site of damage, is always exposed to an oxygenated condition, and the oxygenExpand
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Gene expression analysis of a murine model with pulmonary vascular remodeling compared to end-stage IPAH lungs
BackgroundIdiopathic pulmonary arterial hypertension (IPAH) continues to be one of the most serious intractable diseases that might start with activation of several triggers representing the geneticExpand
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N-acetylated α-linked acidic dipeptidase is identified as an antigen of Histoplasma capsulatum.
Histoplasmosis, one of the most important mycoses, needs to be diagnosed rapidly and accurately. The main method used to diagnose histoplasmosis is serological detection of antibodies to theExpand
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[Candidates for virulence factors of Aspergillus fumigatus].
The number of patients with invasive fungal infection (IFI) has dramatically increased since the beginning of the 1980s. Aspergillus fumigatus, the most common species recovered from aspergillosis,Expand
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Mycoses caused by the inhalation of mycotoxin-producing-fungi growing indoors
屋内環境中には多種多様な真菌が生息している。これらの真菌の多くはマイコトキシンを産生するが、マイコトキシンとヒト疾患との関連性については未解明の点が多い。例外としては、近年、Aspergillus fumigatus によって産生されるグリオトキシンがアスペルギルス症の発症に関与していることが明らかにされた例がある。Stachybotrys chartarumExpand
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