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Tetrahydrobiopterin (BH4) is an essential cofactor for various enzymes in mammals. In vivo, it is synthesized from GTP via the three-step pathway of GTP cyclohydrolase I (GCHI), 6-pyruvoyl-tetrahydropterin synthase (PTPS) and sepiapterin reductase (SPR). BH4 is a medicine used to treat atypical hyperphenylalaninemia. It is currently synthesized by chemical(More)
This paper proposes a system for social reading based on EPUB3, a standardized format for EPUB publications. The system is to collect and manage reading-related information, such as EPUB publications' metadata, bookmarks, and annotations, as well as users' behavioral information, such as the time and the location at which the users read the e-books, the(More)
We propose in this paper a social reading system for EPUB3 publications (SRS4ePub), whereby users can share bookmarks and annotations among users. One of the features of this system is that it fully exploits EPUB and its related open standards to make social reading system possible. Besides, the system can record users' operational records so that we can(More)
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