Ergün Topal

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BACKGROUND Slow coronary flow (SCF) in a normal coronary angiogram is a well-recognized clinical entity, but its etiopathogenesis remains unclear. DESIGN The aim of the study was to determine endothelial function in patients with SCF using a flow-mediated dilatation (FMD) technique in the brachial artery. METHODS Coronary flow was quantified using the(More)
Both experimental and clinical studies suggest that the prehospital administration of aspirin may be beneficial in patients with unstable angina and acute myocardial infarction. Experimental studies indicate that within 1 hour of aspirin administration, serum levels peak and significant inhibition of platelet aggregation occurs. Clinical studies demonstrate(More)
OBJECTIVE Alterations in aortic stiffness may reflect the elastic properties of the larger arteries. In many diseases, aortic elastic properties have been investigated to show whether the larger arteries are involved. The elastic properties of aorta in patients with coronary artery ectasia, however, have not been studied yet. We aimed to investigate aortic(More)
OBJECTIVE The urocortin (Ucn) hormones have many important roles in the cardiovascular system. Apart from systolic dysfunction (SD), there is no sufficient data on the relationship between serum Ucn-2 and diastolic dysfunction (DD), or coronary artery disease (CAD). We investigated serum Ucn-2 levels in SD, DD, and CAD. METHODS In this observational(More)
OBJECTIVE Myocardial dysfunction in patients with cardiomyopathy is proposed to occur due to membrane changes caused by oxidative stress. In our study we evaluate whether there is any relation between the degree of myocardial dysfunction and antioxidant enzymes. METHODS We studied superoxide dismutase (SOD), glutathione peroxidase (GSHPx) and catalase(More)
In addition to coronary atherosclerotic disease, coronary thromboembolism can also lead to acute coronary syndromes. However, coronary thromboembolism due to prosthetic heart valves is very rare and not very well-known. It have been reported only a few cases. In this paper, we present a rare case with vasospastic angina pectoris secondary to coronary(More)
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