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We report the application of single-molecule-based sequencing technology for high-throughput profiling of histone modifications in mammalian cells. By obtaining over four billion bases of sequence from chromatin immunoprecipitated DNA, we generated genome-wide chromatin-state maps of mouse embryonic stem cells, neural progenitor cells and embryonic(More)
A fundamental aspect of all biological systems is cooperation. Cooperative interactions are required for many levels of biological organization ranging from single cells to groups of animals. Human society is based to a large extent on mechanisms that promote cooperation. It is well known that in unstructured populations, natural selection favours defectors(More)
We present a new edition of the Google Books Ngram Corpus, which describes how often words and phrases were used over a period of five centuries, in eight languages; it reflects 6% of all books ever published. This new edition introduces syntactic annotations: words are tagged with their part-of-speech, and head-modifier relationships are recorded. The(More)
Human language is based on grammatical rules. Cultural evolution allows these rules to change over time. Rules compete with each other: as new rules rise to prominence, old ones die away. To quantify the dynamics of language evolution, we studied the regularization of English verbs over the past 1,200 years. Although an elaborate system of productive(More)
Human populations are both highly cooperative and highly organized. Human interactions are not random but rather are structured in social networks. Importantly, ties in these networks often are dynamic, changing in response to the behavior of one's social partners. This dynamic structure permits an important form of conditional action that has been explored(More)
* This cover page was not filed with the Court. The remaining pages are as filed with the Court on July 10, 2014. The authors are acting in their individual capacity and not on behalf of their institutions. individually and on behalf of all others similarly situated Plaintiffs-Appellants HERBERT MITGANG, DANIEL HOFFMAN, individually and on behalf of all(More)
  • Lydia B Chilton, Robert C Miller, Arthur C Smith, Anna Dreber Almenberg, Erez Lieberman, David Rand
  • 2009
The author hereby grants to M.I.T. permission to reproduce and to distribute publicly paper and electronic copies of this thesis document in whole and in part in any medium now known or hereafter created. Abstract Seaweed is a web application for experimental economists with no programming background to design two‐player symmetric games in a visual‐oriented(More)
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