Er-zhen Li

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Tryptophan hydroxylase-2 (TPH2) is a potential candidate gene for screening tic disorder (TD). A case–control study was performed to examine the association between the TPH2 gene and TD. The Sequenom® Mass ARRAY iPLEX GOLD System was used to genotype two single nucleotide polymorphisms (SNPs) of the TPH2 gene in 149 TD children and in 125 normal controls.(More)
OBJECTIVE To find out the rate of comorbidities of depression, anxiety disorder and attention deficit hyperactivity disorder (ADHD) symptoms in children with epilepsy and to analyze the relevant affecting factors and impacts on quality of life. METHOD Totally 142 children with various types of epilepsy underwent neuropsychological assessment with the(More)
OBJECTIVE To study the cognitive function, its correlation with and the impact on quality of life in epileptic children aged 6-13 years in regular school. METHOD Cognitive function of 172 children with various types of epilepsy were measured using a computerized neuropsychological test battery including six items. Their scores across the(More)
BACKGROUND Streptococcal infection and basal ganglia inflammation are hypothesized to be involved in Tourette's syndrome (TS). There is a need for effective therapies for managing TS. We studied streptococcal infection and immunity in TS following immunomodulator (pidotimod) therapy. METHODS Blood samples from 58 patients with TS and 128 age-matched(More)
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