Eoin O'Connell

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The purpose of this investigation was to determine the energy requirement of simulated stair climbing. Metabolic costs of climbing stairs in getting to the scene of a fire can be very demanding for fire personnel. Heart rate and oxygen consumption were measured on 17 fire fighters during each of three conditions: (1) stair climbing without fire-fighting(More)
AIMS Differentiation of heart failure with reduced (HFrEF) or preserved (HFpEF) ejection fraction independent of echocardiography is challenging in the community. Diagnostic strategies based on monitoring circulating microRNA (miRNA) levels may prove to be of clinical value in the near future. The aim of this study was to identify a novel miRNA signature(More)
This prospective investigation was done to evaluate five strength and fitness measurements and the subsequent occurrence of back injuries in 1652 firefighters for the years 1971 to 1974. The prospective measurements included flexibility, isometric lifting strength, bicycle ergometer exercise measurements of two-minute recovery heart rate, diastolic blood(More)
AIMS Prevention of cardiovascular disease and heart failure (HF) in a cost-effective manner is a public health goal. This work aims to assess the cost-effectiveness of the St Vincent's Screening TO Prevent Heart Failure (STOP-HF) intervention. METHODS AND RESULTS This is a substudy of 1054 participants with cardiovascular risk factors [median age 65.8(More)
IMPORTANCE Prevention strategies for heart failure are needed. OBJECTIVE To determine the efficacy of a screening program using brain-type natriuretic peptide (BNP) and collaborative care in an at-risk population in reducing newly diagnosed heart failure and prevalence of significant left ventricular (LV) systolic and/or diastolic dysfunction. DESIGN,(More)
Background- Aspirin use in heart failure (HF) is controversial. The drug has proven benefit in comorbidities associated with HF; however, retrospective analysis of angiotensin-converting enzyme inhibitor trials and prospective comparisons with warfarin have shown increased risk of morbidity with aspirin use. This study aims to evaluate the association of(More)
AIMS Heart failure has been demonstrated in previous studies to have a dismal prognosis. However, the modern-day prognosis of patients with new onset heart failure diagnosed in the community managed within a disease management programme is not known. The purpose of this study is to report on prognosis of patients presenting with new onset heart failure in(More)
OBJECTIVE The most common cause of death in diabetes mellitus is cardiovascular disease. Patients frequently undergo vascular intervention such as stenting. The occurrence of in stent restenosis (ISR) has been reduced by the use of drug eluting stents in non-diabetic patients but the incidence of restenosis and stent thrombosis remains higher in diabetic(More)
CONTEXT Natriuretic peptide (NP) has been shown to be an effective screening tool to identify patients with Stage B heart failure and to have clinical value in preventing heart failure progression. The impact of associated metabolic confounders on the screening utility of NP needs clarification. OBJECTIVE To assess the impact of diabetes mellitus (DM) on(More)