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OBJECTIVE The objective of the present study was to assess factors related to long-term changes in urinary albumin excretion (UAE) of nondiabetic microalbuminuric (n = 252) or proteinuric hypertensive individuals (n = 58) in a prospective follow-up. METHOD After enrollment, patients were placed on usual care including nonpharmacological treatment and/or(More)
BACKGROUND AND OBJECTIVE The aim of this study was to compare the clinical and treatment implications of 2 cardiovascular risk stratification systems in a population of patients 40-65 years old. PATIENTS AND METHOD 929 non diabetic patients (40-65 years old) (51% female) with no evidence of previous cardiovascular disease were included in the study. The(More)
The objective was to assess the temporal impact of factors related to the development of microalbuminuria during the follow-up of young adult normoalbuminurics with high-normal blood pressure or at stage 1 of essential hypertension. Prospective follow-up was conducted on 245 normoalbuminuric hypertensive subjects (mean age 40.9 years; 134 men; blood(More)
BACKGROUND AND OBJECTIVE The aim of the study was to assess the association of serum uric acid levels with microalbuminuria -urinary albumin excretion (UAE)> or = 30mg/24h-. PATIENTS AND METHOD Cross-sectional study in 429 (220 women) hypertensive, non diabetic, never treated patients (mean age: 47 years) with glomerular filtration rate > or(More)
BACKGROUND AND OBJECTIVE The aim of the study was to assess the effect of adding spironolactone to hypertensive resistant (HTR) patients and characterize those who respond effectively. PATIENTS AND METHOD Observational retrospective study on outpatients with HTR (being treated with at least 3 drugs at full doses, one of these being a diuretic) not(More)
OBJECTIVE C-reactive protein (CRP) is considered a marker of subclinical atherosclerosis. The aim of the study was to assess whether the metabolic syndrome (MS) and parameters involved in its diagnosis might influence serum CRP values. PATIENTS AND METHOD Cross-sectional study in outpatients of a HTA and Vascular Risk clinic. MS was diagnosed according to(More)
BACKGROUND AND OBJECTIVES The purpose of the present study was to assess the relationship of arterial stiffness with other markers of target organ damage, and the clinical factors related to it. PATIENTS AND METHODS Cross-sectional study that included 208 (115 men) never treated hypertensive, non-diabetic patients (mean age, 49+/-12 years). In addition to(More)
BACKGROUND Left ventricular hypertrophy is an important predictor of cardiovascular risk and its detection contributes to risk stratification. However, echocardiography is not a routine procedure and electrocardiography (ECG) underestimates its prevalence. OBJECTIVE To evaluate the prevalence of echocardiographic left ventricular hypertrophy in low and(More)
INTRODUCTION The main objective was to compare the mean change in augmentation index of hypertensive patients treated with nebivolol or atenolol. METHODS Multicenter, double-blind randomized study conducted in six Spanish centers. We enrolled outpatients between the ages of 40 and 65 years with mild or moderate essential hypertension (systolic blood(More)
INTRODUCTION AND OBJECTIVES The aim of this study was to evaluate the use of spironolactone and doxazosin as treatment for patients with resistant hypertension. METHODS This retrospective study involved 181 outpatients with resistant hypertension (defined as a failure of blood pressure [BP] control despite treatment with three drugs, one of which was a(More)