Learn More
Anterior body pattern in Drosophila is specified by the graded distribution of the bicoid protein (bcd), which activates subordinate genes in distinct anterior domains. Subsequently, transcription of these target genes is repressed at the anterior pole owing to the activity of the receptor tyrosine kinase torso (tor). We show that both activation by bcd and(More)
Following exposure to short daylengths, in golden hamsters, changes in basal adrenal glucocorticoid secretion are associated with a significant increase in Type I receptor binding, and are preceded by alterations in the stress-induced release of glucocorticoids, which is one of the major modes of operation of the hypothalamo-pituitary-adrenocortical axis(More)
In an effort to understand the potential neuroendocrine mechanisms underlying photoperiodic control of fertility in seasonally breeding species, we monitored the intracellular processing and nuclear uptake of [1 alpha, 2 alpha-3H]testosterone (3H-T) within the brain-pituitary complex as well as the patterns of episodic luteinizing hormone (LH) secretion in(More)
An in situ hybridization assay, utilizing a free floating technique was used to estimate the steady state levels of hypothalamic luteinizing hormone-releasing hormone (GnRH) mRNA levels in the brains of male golden hamsters maintained in different photoperiods. In situ histochemistry was performed using a 32P-labelled 66-nucleotide long oligomer(More)
Hypothalamic luteinizing-hormone-releasing hormone (GnRH) and gonadotropin-releasing-hormone-associated peptide (GAP) biosynthesis and storage were estimated by immunocytochemistry in male golden hamsters maintained in different photoperiods. Intact or castrated male hamsters with subcutaneously inserted testosterone implants were exposed to long-day(More)
in fire. Virtual environments provide a maximum of experimental control, are easy to replicate, have relatively high ecological validity, and allow safe study of occupant behavior in scenarios that otherwise would be too dangerous. Lower ecological validity compared to field studies, ergonomic aspects, and technical limitations are the main weaknesses of(More)
Certain commercial entities, equipment, or materials may be identified in this document in order to describe an experimental procedure or concept adequately. Such identification is not intended to imply recommendation or endorsement by the National Institute of Standards and Technology, nor is it intended to imply that the entities, materials, or equipment(More)
Keywords: Fire evacuation Social influence Travel paths Tunnel fire Virtual reality Functional analysis Region of interest analysis a b s t r a c t Introduction: Evacuation from tunnel fire emergencies requires quick decision-making and swift action from the tunnel occupants. Social influence (SI) has been identified as an important factor in evacuation.(More)
A review of literature related to fire evacuation in high-rise buildings was carried out with the following objectives, (1) to identify the key behavioural factors affecting the performance of people during a fire in a high-rise building, the singularities associated to this type of buildings and areas of future research; (2) to review the procedures and(More)