Enrico Pellegrini

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This paper summarizes three recent, novel algorithms developed within VAMPIRE, namely optic disc and macula detection, arteryvein classification, and enhancement of binary vessel masks, and their performance assessment. VAMPIRE is an international collaboration growing a suite of software tools to allow efficient quantification of morphological properties(More)
Segmentation of perivascular spaces (PVS) from brain magnetic resonance images (MRI) is important for understanding the brain’s lymphatic system and its relationship with neurological diseases. The Frangi filter might be a valuable tool for this purpose. However, its parameters need to be adjusted in response to the variability in scanner’s parameters and(More)
The paper presents the realization of a new suspension system and the experimental validation of a novel adaptive suspension control approach based on an adaptive reference model. The proposed “hybrid” suspension system includes a continuously variable hydraulic semi-active damper as well as an actuator in series to the suspension’s primary spring and can(More)
We explore post-processing of scanning laser ophthalmoscope (SLO) images for the automatic detection of retinal blood vessels. The retinal vasculature is first enhanced using morphological and Gaussian matched filters before a thresholding technique produces a binary vessel map. Such permutations of post-processing techniques are commonly used to achieve(More)
This study concerns with the application of multi-objective H<inf>&#x221E;</inf>/GH<inf>2</inf> preview control to a real quarter vehicle suspension system. To this goal both linear and nonlinear models of the test rig are derived, and a unified design framework for preview design schemes of LQG-preview and multi-objective preview is introduced. Simulations(More)
Features of the retinal vasculature, such as vessel widths, are considered biomarkers for systemic disease. The aim of this work is to present a supervised approach to vessel segmentation in ultra-wide field of view scanning laser ophthalmoscope (UWFoV SLO) images and to evaluate its performance in terms of segmentation and vessel width estimation accuracy.(More)
The paper presents a two degrees of freedom (2-dof) structure combining a dynamic feedforward approach with a nonlinear feedback component to control the damper valves' currents of a semi-active suspension system. The concept makes use of a dynamic damper model, which is able to represent the dynamic behavior significantly more accurate than the standard(More)
INTRODUCTION The ease of imaging the retinal vasculature, and the evolving evidence suggesting this microvascular bed might reflect the cerebral microvasculature, presents an opportunity to investigate cerebrovascular disease and the contribution of microvascular disease to dementia with fundus camera imaging. METHODS A systematic review and meta-analysis(More)
Two optimal control methods for a nonlinear semi-active suspension system subject to state and actuating constraints are presented and compared with LQR and skyhook control. Nonlinearities in the suspension system are considered in terms of variable kinematic transmission factor, bump stops and asymmetric and degressive continously variable damper(More)