Enrica Bonanni

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STUDY OBJECTIVES To verify the existence of a symptomatic form of restless legs syndrome (RLS) secondary to multiple sclerosis (MS) and to identify possible associated risk factors. DESIGN Prospective, multicenter, case-control epidemiologic survey. SETTINGS Twenty sleep centers certified by the Italian Association of Sleep Medicine. PATIENTS Eight(More)
The increased tendency to fall asleep during the daytime together with increased wakefulness during the night has been demonstrated in patients with advanced Alzheimer's disease (AD). The aim of this study was to assess daytime sleep propensity in a cohort of patients with mild/moderate AD and to correlate it with cognitive impairment. Twenty drug-free AD(More)
BACKGROUND/AIMS Sleep disturbances are common in the elderly and in persons with cognitive decline. The aim of this study was to describe frequency and characteristics of insomnia, excessive daytime sleepiness, sleep-disordered breathing, REM behavior disorder and restless legs syndrome in a large cohort of persons with mild cognitive impairment or(More)
PURPOSE The frequency of dream recall (DR) in patients with brain diseases has proved to be indicative of the relation between sleep disturbances and the functioning of cognitive processes during sleep. In this study we attempted to ascertain whether DR frequency in patients with complex partial seizures (CPSs) is higher than that in those with generalized(More)
OBJECTIVE To assess the effects of Alzheimer's disease (AD) and Mild Cognitive Impairment (MCI) on simulated car driving ability. METHODS Twenty patients with a probable AD of mild severity (Clinical Dementia Rating, CDR = 1) were compared with 20 subjects with MCI (CD = 0.5), and a group of age-matched neurologically normal controls on a driving(More)
OBJECTIVES The aim of this research has been to introduce an automatic method, simple from the mathematical and computational points of view, for the recognition and classification of the A-phases of the cyclic alternating pattern. METHODS The automatic method was based on the computation of 5 descriptors, which were derived from the EEG signal and were(More)
BACKGROUND Conversely to other neurodegenerative diseases (i.e., Alzheimer's disease, AD), sleep in frontotemporal dementia (FTD) has not been studied adequately. Although some evidence exists that sleep-wake disturbances occur in FTD, very little is known regarding sleep macrostructure and/or primary sleep disorders. OBJECTIVE To investigate these issues(More)
OBJECTIVES The goal of this study was to determine if vagus nerve stimulation (VNS) has any effect on daytime vigilance and perceived sense of well-being. METHODS Multiple Sleep Latency Tests (MSLTs) were performed and visual reaction times (VRTs) obtained in eight epileptic patients before and during treatment with VNS. Prior to VNS initiation patients'(More)
BACKGROUND Bullous pemphigoid (BP) is a blistering skin disease caused by autoantibodies to hemidesmosomal proteins, with eosinophils participating in blister formation. Eosinophils are a source of tissue factor (TF), an initiator of blood coagulation. OBJECTIVES To evaluate the local and systemic activation of coagulation in BP. METHODS We studied 20(More)
This study examined the effectiveness of the cognitive processes underlying dreaming in patients with complex partial seizures (CPS), by assessing the frequency of recall and the structural organization of dreams reported after awakenings provoked alternately during REM and stage 2 NREM sleep on 12 cognitively unimpaired CPS-patients (six with epileptic(More)