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PURPOSE To investigate the potential role of caspase-3 in blue light-induced apoptosis in photoreceptor cells. METHODS Cyclic light-raised Sprague-Dawley rats were exposed to 400 to 480 nm light for 6 hours at an irradiance of 0.64 W/m(2). The rats were then kept in darkness for recovery and killed at scheduled time points from 0 hours up to 24 hours(More)
  • E Chen
  • 1993
The activity of cytochrome oxidase, outer nuclear layer thickness, and edema were quantitatively evaluated in the blue-light exposed rat retina. Dark-adapted or cyclic-light reared rats were exposed to blue light with a retinal dose of 380 kJ/m2. Immediately, 1, 2, and 3 day(s) after exposure, the retinas of six rats from each adaptation group were(More)
Cytochrome oxidase (CYO), a key enzyme in the respiratory chain, was observed as an indicator of retinal metabolism after an in vivo blue light exposure. Thirty Sprague-Dawley rats were exposed to optic radiation of 404 nm with a retinal dose of 110kJ/m2. Immediately after exposure, the CYO activity in the pigment epithelium, in the outer and inner segments(More)
BACKGROUND AND OBJECTIVE The aim of the present study was to compare intraocular pressure (IOP) reduction and inflammation after selective laser trabeculoplasty (SLT) treatment in patients suffering from primary open angle (POAG) vs pseudoexfoliative (PXFG) glaucoma. STUDY DESIGN/PATIENTS AND METHODS Sixty patients (60 eyes) participated in the study.(More)
PURPOSE Glaucoma is a progressive optic neuropathy that may lead to blindness. Reducing intraocular pressure (IOP) is the only known treatment to slow progression in glaucoma. IOP can be reduced by pharmaceutical treatment, laser and surgery. The aim of the present study was to assess predictive factors of success after selective laser trabeculoplasty (SLT)(More)
PURPOSE Glaucoma is a progressive optic neuropathy that may lead to blindness. Reducing intraocular pressure (IOP) seems to be the only treatment that slows progression in glaucoma. IOP can be decreased by pharmaceutical treatment, laser treatment or surgery. The aim of the present study was to assess the long-term efficacy of selective laser(More)
Cytochrome oxidase (CYO) is a key enzyme in the respiratory chain. Therefore, CYO has an important role in the cell metabolism. In the present study CYO activity in the rat retina was identified by histochemical staining. The density of the staining, corresponding to the activity of the CYO, was evaluated quantitatively by densitometry. A high CYO activity(More)
BACKGROUND The aim of this study was to determine a threshold waveform score (WS) for the best score value (BSV) in the Ocular Response Analyzer (ORA). METHODS Retrospective study. One hundred and thirty-three healthy adults were recruited. Measurements were done with the ORA 2.04. RESULTS Two hundred and sixty-six eyes were analyzed. Mean age was 56.49(More)
A method for the calibration of gray scale density in a Scheimpflug photograph was established. Based on the result of statistical analysis, it was found that variability in the film emulsion was insignificant if the measuring area > or = 0.01 mm2. Each lens image should be calibrated with the reference gray scale in the same photograph. Photometric(More)
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