Emmanuelle Germain

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BACKGROUND Although several anti-angiogenic therapies have been approved in the treatment of cancer, the survival benefits of such therapies are relatively modest. Discovering new molecules and/or better understating signaling pathways of angiogenesis is therefore essential for therapeutic improvements. The objective of the present study was to determine(More)
PURPOSE Given that nerve growth factor has previously been shown to be involved in breast cancer progression, we have tested here the hypothesis that the other neurotrophins (NT) are expressed and have an influence in breast tumor growth. EXPERIMENTAL DESIGN The expression of brain-derived neurotrophic factor (BDNF), NT-3 and NT-4/5, as well as the(More)
Purpose: Given that nerve growth factor has previously been shown to be involved in breast cancer progression, we have tested here the hypothesis that the other neurotrophins (NT) are expressed and have an influence in breast tumor growth. immunohistochemistry in cell lines and tumor biopsies. The biological impacts of neurotrophins, and associated(More)
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