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Risk factors for acute myocardial infarction in Indians: a case-control study.

• Priya Pais, Janice Pogue, +5 authors Shehu Mohammed Yusuf
• Lancet
• 1996

BACKGROUND South Asians who have settled overseas and those in urban India have an increased risk of ischaemic heart disease (IHD). Reasons for this increased risk are unclear. Most studies have been… (More)

Effects of 10 mg and 15 mg oral procyclidine on critical flicker fusion threshold and cardiac functioning in healthy human subjects.

• T. Virajita Sharma, Anna M. Galea, +4 authors Veena Kumari
• Journal of psychopharmacology
• 2002

The critical flicker fusion threshold (CFFT) is thought to index alertness and cortical arousal. Sedative drugs reduce CFFT while psychostimulants increase it. Procyclidine is an anticholinergic that… (More)

Plasma estradiol and lipid profile in perimenopausal women.

• L Kalavathi, H R Dhruvanarayan, Emmanuel Zachariah
• Indian journal of physiology and pharmacology
• 1991

This study was conducted to examine the estradiol level and plasma lipid profile in perimenopausal women. The estradiol and HDL levels were higher and LDL levels lower in premenopausal women than in… (More)

Cognitive functioning in siblings discordant for schizophrenia.

• C. Hughes, Veena Kumari, +4 authors T. Sharma
• Acta psychiatrica Scandinavica
• 2005

OBJECTIVE The objective of this study was to investigate neuropsychological impairment as a genetically mediated risk indicator for schizophrenia while accounting for prevalence of schizotypy… (More)

Probing oxidative stress in single erythrocytes with Raman Tweezers.

• Emmanuel Zachariah, Asma R. Bankapur, C. Santhosh, Mohan Valiathan, Deepak Mathur
• Journal of photochemistry and photobiology. B…
• 2010

Raman Tweezers have been successfully applied to characterize chemically-induced oxidative stress on optically-trapped live, single erythrocytes. There is significant enhancement in Raman peak… (More)

GROalpha is highly expressed in adenocarcinoma of the colon and down-regulates fibulin-1.

• Yu Wen, Sarah F Giardina, +10 authors Daniel A. Notterman
• Clinical cancer research : an official journal of…
• 2006

PURPOSE The growth-related oncogene alpha (GROalpha) is a secreted interleukin-like molecule that interacts with the CXCR2 G-protein-coupled receptor. We found that the mRNA and protein products of… (More)

Effects of procyclidine on prepulse inhibition of the acoustic startle response in healthy human volunteers

• Veena Kumari, Emmanuel Zachariah, Anna M. Galea, R. Mehrotra, D. Taylor, T. Sharma
• Psychopharmacology
• 2001

Rationale: Prepulse inhibition (PPI) of the startle response refers to an attenuation in response to a strong stimulus (pulse) if this is preceded shortly by a weak non-startling stimulus (prepulse).… (More)

High incidence of LRAT promoter hypermethylation in colorectal cancer correlates with tumor stage.

• Yu-Wei Cheng, Hanna Pincas, +5 authors Francis Barany
• Medical oncology
• 2014

Lecithin:retinol acyltransferase (LRAT) is a major enzyme involved in vitamin A/retinol metabolism, which regulates various physiological processes like cell proliferation and differentiation. LRAT… (More)

A Support Vector Machine based Prediction Model for Discrimination of Malignant Pulmonary Nodules from Benign Nodules

• Yan Wu, Emmanuel Zachariah, +10 authors David J. Foran
• BIOIMAGING
• 2016

Transcriptomic analysis of pancreatic cancer cells in response to metformin and aspirin: an implication of synergy

• Wen Yue, Tao Wang, +5 authors Xiang-Lin Tan
• Scientific reports
• 2015

Metformin and aspirin have been studied extensively as cancer preventative and therapeutic agents. However, the underlying molecular mechanisms for the inhibitory effects of pancreatic cancer… (More)

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