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- Maxime D Guillemette, Bo Cui, +10 authors François A Auger
- Integrative biology : quantitative biosciences…
- 2009

The organization of cells and extracellular matrix (ECM) in native tissues plays a crucial role in their functionality. However, in tissue engineering, cells and ECM are randomly distributed within a scaffold. Thus, the production of engineered-tissue with complex 3D organization remains a challenge. In the present study, we used contact guidance to control… (More)

- Emmanuel Roy
- 2008

We show that a stationary IDp process (i.e., an infinitely divisible stationary process without Gaussian part) can be written as the independent sum of four stationary IDp processes, each of them belonging to a different class characterized by its Lévy measure. The ergodic properties of each class are, respectively, nonergodicity, weak mixing, mixing of all… (More)

We use the Poisson cluster process structure of a Hawkes process to derive non asymptotic estimates of the tail of the extinction time, of the coupling time or of the number of points per interval. This allows us to define a family of independent Hawkes processes ; each of them approximating the initial process on a particular interval. Then we can easily… (More)

- Joseph M. Gallagher, Hiba Komati, Emmanuel Roy, Mona Nemer, Branko V. Latinkić
- Molecular and cellular biology
- 2012

Transcription factor GATA4 is a critical regulator of the embryonic and postnatal heart, but the mechanisms and cofactors required for its diverse functions are not fully understood. Here, we show that whereas the N-terminal domain of GATA4 is required for inducing cardiogenesis and for promoting postnatal cardiomyocyte survival, distinct residues and… (More)

- Gerardo A. Diaz-Quijada, Régis Peytavi, +4 authors Teodor Veres
- Lab on a chip
- 2007

Microarrays have become one of the most convenient tools for high throughput screening, supporting major advances in genomics and proteomics. Other important applications can be found in medical diagnostics, detection of biothreats, drug discovery, etc. Integration of microarrays with microfluidic devices can be highly advantageous in terms of portability,… (More)

- Marc Herrmann, Emmanuel Roy, Teodor Veres, Maryam Tabrizian
- Lab on a chip
- 2007

Achieving efficient passivation of micro-channels against non-specific adsorption of biomolecules is a critical aspect in the development of microfluidic ELISA systems. Usual surface treatments such as pre-coating of the channels with serum albumin, exposure to oxygen plasma, polyethylene glycol grafting however exhibit a lack of long-term stability, with… (More)

The Poisson entropy of an infinite-measure-preserving transformation is defined in [13] as the Kolmogorov entropy of its Poisson suspension. In this article, we relate Poisson entropy with other definitions of entropy for infinite transformations: For quasi-finite transformations we prove that Poisson entropy coincides with Krengel’s and Parry’s entropy… (More)

- Emmanuel Roy, Gale Stewart, +7 authors Teodor Veres
- Lab on a chip
- 2015

We present an all-thermoplastic integrated sample-to-answer centrifugal microfluidic Lab-on-Disc system (LoD) for nucleic acid analysis. The proposed CD system and engineered platform were employed for analysis of Bacillus atrophaeus subsp. globigii spores. The complete assay comprised cellular lysis, polymerase chain reaction (PCR) amplification, amplicon… (More)

- Matthias Geissler, Emmanuel Roy, Gerardo A. Diaz-Quijada, Jean-Christophe Galas, Teodor Veres
- ACS applied materials & interfaces
- 2009

This paper describes the patterning of DNA arrays on plastic surfaces using an elastomeric, two-dimensional microcapillary system (muCS). Fluidic structures were realized through hot-embossing lithography using Versaflex CL30. Like elastomers based on poly(dimethylsiloxane), this thermoplastic block copolymer is able to seal a surface in a reversible… (More)

- Emmanuel Roy, Jean-Christophe Galas, Teodor Veres
- Lab on a chip
- 2011

Multilayer soft lithography of polydimethylsiloxane (PDMS) is a well-known method for the fabrication of complex fluidic functions. With advantages and drawbacks, this technique allows fabrication of valves, pumps and micro-mixers. However, the process is inadequate for industrial applications. Here, we report a rapid prototyping technique for the… (More)