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Genome analysis of the platypus reveals unique signatures of evolution
This corrects the article DOI: 10.1038/nature06936
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The rise, fall and renaissance of microsatellites in eukaryotic genomes.
Microsatellites are among the most versatile of genetic markers, being used in an impressive number of biological applications. However, the evolutionary dynamics of these markers remain a source ofExpand
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Genome analysis of the platypus reveals unique signatures of evolution
We present a draft genome sequence of the platypus, Ornithorhynchus anatinus. This monotreme exhibits a fascinating combination of reptilian and mammalian characters. For example, platypuses have aExpand
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Rapid Evolution of Coral Proteins Responsible for Interaction with the Environment
Background Corals worldwide are in decline due to climate change effects (e.g., rising seawater temperatures), pollution, and exploitation. The ability of corals to cope with these stressors in theExpand
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Microsatellite Tandem Repeats Are Abundant in Human Promoters and Are Associated with Regulatory Elements
Tandem repeats are genomic elements that are prone to changes in repeat number and are thus often polymorphic. These sequences are found at a high density at the start of human genes, in the gene’sExpand
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Conservation of Human Microsatellites across 450 Million Years of Evolution
The sequencing and comparison of vertebrate genomes have enabled the identification of widely conserved genomic elements. Chief among these are genes and cis-regulatory regions, which are often underExpand
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Evolution of Microsatellite DNA
Microsatellites are highly mutable nucleotide arrays composed of short motifs repeated in tandem. They are ubiquitously distributed in bacterial and eukaryotic genomes and their abundance andExpand
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Measuring Microsatellite Conservation in Mammalian Evolution with a Phylogenetic Birth–Death Model
Microsatellites make up ∼3% of the human genome, and there is increasing evidence that some microsatellites can have important functions and can be conserved by selection. To investigate thisExpand
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Promoter microsatellites as modulators of human gene expression.
Microsatellites in and around genes have been shown to modulate levels of gene expression in multiple organisms, ranging from bacteria to humans. Here we will discuss promoter microsatellites knownExpand
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Development of microsatellite markers for the short-beaked echidna using three different approaches
Abstract. We used three different methods, size-selected genomic library, cross-species amplification of a mammal-wide set of conserved microsatellites and genomic sequencing, to develop a panel ofExpand
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