Emmanuel A. Stamatakis

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Knowledge of objects in the world is stored in our brains as rich, multimodal representations. Because the neural pathways that process this diverse sensory information are largely anatomically distinct, a fundamental challenge to cognitive neuroscience is to explain how the brain binds the different sensory features that comprise an object to form(More)
Dissociations of nouns and verbs following brain damage have been interpreted as evidence for distinct neural substrates underlying different aspects of the language system. Some neuroimaging studies have supported this claim by finding neural differentiation for nouns and verbs [Brain 122 (1999) 2337] while others have argued against neural specialisation(More)
How objects are represented and processed in the brain is a central topic in cognitive neuroscience. Previous studies have shown that knowledge of objects is represented in a feature-based distributed neural system primarily involving occipital and temporal cortical regions. Research with nonhuman primates suggest that these features are structured in a(More)
Patients with damage to left anteromedial temporal cortex often show a striking deficit: they fail to recognize animals and other living things. This failure of recognition presents an important challenge to theories of the neural representation of conceptual knowledge. Here we propose that this lesion-behaviour association arises because polymodal neurons(More)
Recent research has indicated that processing different kinds of action verbs, such as those related to arm or leg movements (e.g. grab, kick), engages regions along the motor strip responsible for the execution of the corresponding actions. It has been proposed that this activation reflects action-related meaning and that these regions are automatically(More)
A prominent issue in cognitive neuroscience is whether language function is instantiated in the brain as a single undifferentiated process, or whether regions of relative specialisation can be demonstrated. The contrast between regular and irregular English verb inflection has been pivotal to this debate. Behavioural dissociations related to different(More)
Although widespread neural atrophy is an inevitable consequence of normal aging, not all cognitive abilities decline as we age. For example, spoken language comprehension tends to be preserved, despite atrophy in neural regions involved in language function. Here, we combined measures of behavior, functional activation, and gray matter (GM) change in a(More)
For the past 150 years, neurobiological models of language have debated the role of key brain regions in language function. One consistently debated set of issues concern the role of the left inferior frontal gyrus in syntactic processing. Here we combine measures of functional activity, grey matter integrity and performance in patients with left hemisphere(More)
BACKGROUND The default mode network consists of a set of functionally connected brain regions (posterior cingulate, medial prefrontal cortex and bilateral parietal cortex) maximally active in functional imaging studies under "no task" conditions. It has been argued that the posterior cingulate is important in consciousness/awareness, but previous(More)
The study of neuropsychological disorders has been greatly facilitated by the localization of brain lesions on MRI scans. Current popular approaches for the assessment of MRI brain scans mostly depend on the successful segmentation of the brain into grey and white matter. These methods cannot be used effectively with large lesions because lesions usually(More)