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Heart Rate Variability (HRV) reflects the balance between sympathetic and parasympathetic activity. Slower HRV rhythms (LF) indicate increased sympathetic and/or lower vagal activity, wakefulness characteristics, while faster HRV rhythms (HF) indicate lower sympathetic and/or increased parasympathetic and vagal activity, sleepy characteristics. In this work(More)
This work aims at examining the influence of lorazepam, an anxiolytic drug with sedative effects, on brain activity and specifically on EEG Fractal Dimension (FD). The main objective is to clarify the reasons for FD increase after drug intake and to establish a relationship between FD and EEG energy bands. 14 healthy subjects that received either 2.5mg of(More)
— Non-invasive monitoring of a patient's vital signs outside the medical centre is essential for the remote management of chronic cardiovascular diseases (CVD), such as Heart Failure (HF) and Coronary Artery Disease (CAD). In this work we present preliminary results from pre-clinical testing of the IMAGE sensing platform, a wearable device which we designed(More)
The HeartCycle EU research project aims to provide disease management solutions for cardiac patients. Developed within HeartCycle, IMAGE is a wearable device capable of acquiring ECG, bioimpedance, and acceleration measurements. The acquired signals are stored in onboard memory and processed, while the results are wirelessly transmitted in real time to a(More)
This paper presents a complete framework for automatic detection of malignant cells in microscopic images acquired from tissue biopsies of follicular lymphoma. After pre-processing to remove noise and suppress small details, images are segmented by using intensity thresholding, in order to detect the cell nuclei. Subsequently, touching cells are being(More)
This paper presents a new method for discriminating centroblast (CB) from non-centroblast cells in microscopic images acquired from tissue biopsies of follicular lymphoma. In the proposed method tissue sections are sliced at a low thickness level, around 1-1.5 μm, which provides a more detailed depiction of the nuclei and other textural information of cells(More)
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