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OBJECTIVES Following appropriate validation, clinical prediction rules (CPRs) should undergo impact analysis to evaluate their effect on patient care. The aim of this systematic review is to narratively review and critically appraise CPR impact analysis studies relevant to primary care. SETTING Primary care. PARTICIPANTS Adults and children. (More)
BACKGROUND Many people with chronic disease have more than one chronic condition, which is referred to as multimorbidity. The term comorbidity is also used but this is now taken to mean that there is a defined index condition with other linked conditions, for example diabetes and cardiovascular disease. It is also used when there are combinations of defined(More)
The nutritional health of the individual can determine the outcome of wound management. Frequent nutritional assessments must be performed in order to detect patients with malnutrition or at risk of malnutrition. Energy requirements must be calculated for those deemed to be malnourished or at risk of malnourishment. Early intervention is paramount to ensure(More)
Clinical Prediction Rules (CPRs) are tools that quantify the contribution of symptoms, clinical signs and available diagnostic tests, and in doing so stratify patients according to the probability of having a target outcome or need for a specified treatment. Most focus on the derivation stage with only a minority progressing to validation and very few(More)
BACKGROUND Risk prediction models have been developed to identify those at increased risk for emergency admissions, which could facilitate targeted interventions in primary care to prevent these events. OBJECTIVE Systematic review of validated risk prediction models for predicting emergency hospital admissions in community-dwelling adults. METHODS A(More)
BACKGROUND Potentially inappropriate prescribing (PIP) describes medications where risk generally outweighs benefit for older people. Cross-sectional studies suggest an association between PIP and poorer health outcomes but there is a paucity of prospective cohort studies. This study investigates the longitudinal association of PIP with adverse drug events(More)
The CHADS2 predicts annual risk of ischaemic stroke in non-valvular atrial fibrillation. This systematic review and meta-analysis aims to determine the predictive value of CHADS2. The literature was systematically searched from 2001 to October 2010. Data was pooled and analysed using discrimination and calibration statistical measures, using a random(More)
OBJECTIVES To perform a systematic review of the Probability of Repeated Admission (Pra) score in community-dwelling adults to assess its performance in a range of validation studies in the community setting. DESIGN Systematic review and meta-analysis. SETTING Primary and community care. PARTICIPANTS Community-dwelling older people. MEASUREMENTS The(More)