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Expression of Constitutive Androstane Receptor Splice Variants in Human Tissues and Their Functional Consequences
The constitutive androstane receptor (CAR) NR1I3 is a transcription factor that upon activation by xenobiotics induces transcription of drug-metabolizing and drug transporter genes. Our goal was toExpand
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Processing of 3'-extended read-through transcripts by the exosome can generate functional mRNAs.
Strains carrying rna14.1 and rna15.2 mutations are defective in pre-mRNA 3' cleavage, polyadenylation, and transcription termination. Long extended read-through transcripts generated in rna14.1 andExpand
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Quantitative proteomics of heavy metal stress responses in Sydney rock oysters
Currently, there are few predictive biomarkers in key biomonitoring species, such as oysters, that can detect heavy metal pollution in coastal waterways. Several attributes make oysters superior toExpand
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From the Cover: Development and Application of a Dual Rat and Human AHR Activation Assay
Significant prolonged aryl hydrocarbon receptor (AHR) activation, classically exhibited following exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin, can cause a variety of undesirable toxicologicalExpand
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THE PECULIAR KIND OF CLARITY WHICH HELL AFFORDS: DEFINING LOYALTY IN THE WARTIME NORTH, 1860-1865
The focus of this research is on disloyalty investigations during the Civil War. In this research I sought to understand how disloyalty was defined within these loyalty investigations, navigating theExpand
Left Out: A Revealing Look Into the Everyday Fashion Choices of Individuals With Mobility Disabilities
Based on interviews with individuals with mobility disabilities, this thesis argues the lack of mainstream clothing available and the geriatric style of clothing often associated with physicalExpand