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For obese individuals, successful weight loss and maintenance are notoriously difficult. Traditional drug development fails to exploit knowledge of the psychological factors that crucially influence appetite, concentrating instead on restrictive criteria of intake and weight reduction, allied to a mechanistic view of energy regulation. Drugs are under(More)
Over 35 years of research suggests that endogenous hypothalamic serotonin (5-hydroxytryptamine) plays an important part in within-meal satiation and post-meal satiety processes. Thus, the serotonin system has provided a viable target for weight control, critical to the action of at least two effective anti-obesity treatments, both producing clinically(More)
Food advert exposure has been shown to influence calorie intake and food choice in 9-11 year olds. However, little is known about the effect of food advertisements on feeding behaviour in younger children. Therefore, we conducted a study with 93 children aged 5-7 years, 28 of whom were over weight or obese. The children were exposed to 10 non-food adverts(More)
OBJECTIVE To investigate the effect of television food advertising on children's food intake, specifically whether childhood obesity is related to a greater susceptibility to food promotion. DESIGN The study was a within-subject, counterbalanced design. The children were tested on two occasions separated by two weeks. One condition involved the children(More)
The impact of two commercially available products, a patented herb extract Yerbe Maté, Guarana and Damiana (YGD) formulation and an inulin-based soluble fermentable fibre (SFF), alone or in combination, on appetite and food intake were studied for the first time in a double blind, placebo-controlled, cross-over design. 58 normal to slightly overweight women(More)
Consumers report that chewing gum can reduce cravings and the likelihood of snacking. The present study set out to examine the effects of chewing gum on subjective appetite and snack energy intake (EI) in 60 participants (40 females, 20 males, 21.7+/-4 years; BMI=22.7+/-3.4) who came to the laboratory four times for lunch and then returned 3 h later for a(More)
The role of serotonin (5-hydroxytryptamine) in appetite control is long established. Serotonergic manipulations reduce food intake in rodents in a manner consistent with satiety. In humans, drugs such as fenfluramine, dexfenfluramine and sibutramine all reduce energy intake, suppress hunger and enhance satiety. Effects on eating behaviour and subjective(More)
Television provides one of the first, and most intimate, experiences of commercial food promotion. Therefore, unsurprisingly, the effects of television advertising on children's brand preferences are well established. However, its effect on actual food intake and the food choices in children of various weight statuses has only recently been characterised.(More)
Fifty-five women were recruited and assigned to a control group or an oral contraceptive (OC) use group. For the control groups menstrual cycle phase was determined using a menstrual calendar and only participants with regular cycles were recruited. Testing was carried out during a single day of the luteal and follicular phases, where participants were(More)
The aim of this study was to quantify the nature and extent of use of persuasive marketing techniques in television advertisements (adverts) to promote foods to children. Popular UK commercial television channels broadcasting children's/family viewing were recorded for 2 days (6 am-10 pm) every month in 2008 and recordings were screened for adverts.(More)