Emma Essock-Burns

Learn More
Histopathologic evaluation of glioblastoma multiforme (GBM) at initial diagnosis is typically performed on tissue obtained from regions of contrast enhancement (CE) as depicted on gadolinium-enhanced, T1-weighted images. The non-enhancing (NE) portion of the lesion, which contains both reactive edema and infiltrative tumor, is only partially removed due to(More)
BACKGROUND Radiotherapy (RT) is an integral component in managing patients with glioma, but the damage it may cause to healthy brain tissue and quality of life is of concern. Susceptibility-weighted imaging (SWI) is highly sensitive to the detection of microbleeds that occur years after RT. This study's goals were to characterize the evolution of(More)
PURPOSE To compare 2 optical patient interface designs used for femtosecond laser-assisted cataract surgery. SETTING Optimedica Corp., Santa Clara, California, USA, and Centro Laser, Santo Domingo, Dominican Republic. DESIGN Experimental and clinical studies. METHODS Laser capsulotomy was performed during cataract surgery with a curved contact lens(More)
The paradigm for treating patients with glioblastoma multiforme (GBM) is shifting from a purely cytotoxic approach to one that incorporates antiangiogenic agents. These are thought to normalize the tumor vasculature and have shown improved disease management in patients with recurrent disease. How this vascular remodeling evolves during the full course of(More)
BACKGROUND The goal of this study was to investigate whether the amount of hypointense signal on susceptibility-weighted imaging within the contrast-enhancing lesion (%SWI-h) on the pretreatment scan could determine response in patients with newly diagnosed glioblastoma multiforme who received external beam radiation therapy with concomitant anti-angiogenic(More)
PURPOSE To evaluate which common post-processing method applied to gradient-echo DSC-MRI data, acquired with a single gadolinium injection and low flip-angle, most accurately reflects microvascular histopathology for patients with de novo, treatment-naive glioblastoma multiforme (GBM). MATERIALS AND METHODS Seventy-two tissue samples were collected from(More)
This study analyzes the performance of a computer aided detection (CAD) scheme for mass detection in mammography. We investigate the trained parameters of the detection scheme before any further testing. We use an extended version of a previously reported mass detection scheme. We analyze the detection parameters by using linear canonical discriminants(More)
  • 1