Emily L. McGinley

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BACKGROUND Clostridium difficile is an important cause of diarrhoea in hospitalised patients. An increasing number of cases of C difficile colitis occur in patients with inflammatory bowel disease (IBD)-Crohn's disease (CD), ulcerative colitis (UC). OBJECTIVE To estimate the potential excess morbidity and mortality associated with C difficile in(More)
BACKGROUND Severe sepsis is common and often fatal. The expanding armamentarium of evidence-based therapies has improved the outcomes of persons with this disease. However, the existing national estimates of the frequency and outcomes of severe sepsis were made before many of the recent therapeutic advances. Therefore, it is important to study the outcomes(More)
OBJECTIVES:Clostridium difficile–associated disease (CDAD) is associated with antibiotic use, acid suppression, and hospitalization, all of which occur frequently in cirrhosis. The aim was to define the effect of CDAD on outcomes and identify risk factors for its development in cirrhosis.METHODS:Case–control studies using the de-identified national(More)
BACKGROUND Inflammatory bowel disease (IBD) has a bimodal peak of incidence with approximately 15% of the cases manifesting after 65 years. Previous reports on the outcomes of IBD in the elderly have been single-center studies or have predated the use of biologics. The aim of our study was to compare outcomes of IBD-related hospitalizations in a nationwide(More)
PROBLEM/CONDITION Tetanus is a severe and often fatal infection. The incidence of reported cases in the United States has declined steadily since introduction of tetanus toxoid vaccines in the 1940s. REPORTING PERIOD This report covers surveillance data for 1998--2000. DESCRIPTION OF SYSTEM Physician-diagnosed cases of tetanus were reported to CDC's(More)
BACKGROUND & AIMS Previous studies have identified a weekend effect in outcomes of patients with various medical conditions suggesting worse outcomes for weekend admissions. The aim of our study was to analyze if weekend admissions for upper gastrointestinal hemorrhage (UGIH) have higher mortality and longer hospital stay compared with those admitted on(More)
OBJECTIVE Studies in orthodontics have focused primarily on clinical care and techniques. Little, however, has been reported from epidemiological studies using national data on orthodontic dental visits as a measure of orthodontic service utilization and access to care in minority populations. We examined the effect of race/ethnicity and socioeconomic(More)
BACKGROUND Patients hospitalized for ulcerative colitis (UC) are at high risk for colectomy. Despite growing interest in research using administrative data in inflammatory bowel disease, there is no available tool in such research to stratify disease severity or identify patients at high risk for colectomy. METHODS Using the Nationwide Inpatient Sample(More)
BACKGROUND Clostridium difficile has emerged as an important pathogen in patients with inflammatory bowel disease (IBD) and is associated with increased morbidity and mortality. No studies have examined the temporal change in severity of C. difficile infection (CDI) complicating IBD. METHODS Using data from the Nationwide Inpatient Sample, we identified(More)
BACKGROUND Known genetic loci account for less than 25% of the risk for inflammatory bowel disease (IBD), suggesting a potential role for environmental triggers. The association between ambient air pollution and IBD hospitalizations has not been previously studied. METHODS Data from the Wisconsin Hospital Association (WHA) for the year 2002 was used to(More)