Emily G. Richter

Learn More
A comprehensive analysis of both the molecular genetic and phenotypic responses of any organism to the space flight environment has never been accomplished because of significant technological and logistical hurdles. Moreover, the effects of space flight on microbial pathogenicity and associated infectious disease risks have not been studied. The bacterial(More)
In vitro cell culture models used to study how Salmonella initiates disease at the intestinal epithelium would benefit from the recognition that organs and tissues function in a three-dimensional (3-D) environment and that this spatial context is necessary for development of cultures that more realistically resemble in vivo tissues/organs. Our aim was to(More)
The spaceflight environment is relevant to conditions encountered by pathogens during the course of infection and induces novel changes in microbial pathogenesis not observed using conventional methods. It is unclear how microbial cells sense spaceflight-associated changes to their growth environment and orchestrate corresponding changes in molecular and(More)
Representative, reproducible, and high-throughput models of human cells and tissues are critical for a meaningful evaluation of host–pathogen interactions and are an essential component of the research developmental pipeline. The most informative infection models—animals, organ explants, and human trials—are not suited for extensive evaluation of(More)
Department of Physics & Astronomy, Clemson University, Clemson, SC 29634 Zyvex Corporation, Richardson, TX 75081 Department of Physics & Astronomy, University of Kentucky, Lexington, KY 40506 Max-Planck Institute for Solid State Research, 70569 Stuttgart, Germany Department of Physics, Pennsylvania State University, University Park PA 16802, Department of(More)