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AIM Numerous genes are known to cause dilated cardiomyopathy (DCM). However, until now technological limitations have hindered elucidation of the contribution of all clinically relevant disease genes to DCM phenotypes in larger cohorts. We now utilized next-generation sequencing to overcome these limitations and screened all DCM disease genes in a large(More)
BACKGROUND Despite modern pharmacotherapy and advanced implantable cardiac devices, overall prognosis and quality of life of HF patients remain poor. This is in part due to insufficient patient stratification and lack of individualized therapy planning, resulting in less effective treatments and a significant number of non-responders. METHODS AND RESULTS(More)
Siemens and Loral Western Development Labs have designed a Picture Archiving and Communication System capable of supporting a large, fully digital hospital. Its functions include the management, storage and retrieval of medical images. The system may be modeled as a heterogeneous network of processing elements, transfer devices and storage units. A series(More)
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