Emanuela Reale

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The mechanisms by which alcohol consumption worsens the evolution of chronic hepatitis C (CHC) are poorly understood. We have investigated the possible interaction between hepatitis C virus (HCV) and ethanol in promoting oxidative stress. Circulating IgG against human serum albumin (HSA) adducted with malondialdehyde (MDA-HSA), 4-hydroxynonenal (HNE-HSA),(More)
In a patient with hyperkalemic periodic paralysis, metaproterenol prevented muscular weakness and hyperkalemia in periods of rest after exercise. During a severe attack, the drug rapidly corrected hyperkalemia and seemed to enhance the return of strength. The action of metaproterenol may involve a beta-adrenergic-mediated increase of potassium transport via(More)
Despite its relevance for research funding, few comparable data are available in official R&D statistics on the amount and composition of project funding. This paper discusses in detail the methodology developed in the European Network of Excellence on Research and Innovation Policies PRIME for systematically producing indicators on public project funding(More)
The identification of the epitopes recognized by autoantibodies against cytochrome P450s (CYPs) associated with drug-induced hepatotoxicity is difficult because of their conformational nature. In the present investigation, we used a novel approach based on the analysis of the whole molecule antigenic capacity following single amino acid substitutions to(More)
This article presents a comparative analysis of the evolution of national research policies during the past three decades in six European countries (Austria, Italy, France, Netherlands, Norway and Switzerland), with a special focus on the changes of public project funding schemes. It systematically uses indicators on the volume of funding attributed by each(More)
How do Higher Education Institutions respond to steering attempts in different disciplines? How can different responses be explained? Case studies have been developed in the Italian Higher Education context and at the departmental level, with a focus on government interventions through funding and evaluation of research. The paper tests the predictions of(More)
The use of heparin sodium and warfarin sodium in the treatment of pulmonary embolus (PE), deep vein thrombosis (DVT) and thrombophlebitis (TP) was studied by a hospital pharmacy department. During a four-month period, the charts of 26 patients were audited for anticoagulant dosages used; laboratory test monitoring of anticoagulant dosage used; laboratory(More)
Nations, universities, and regional governments commit resources to promote the dissemination of scientific and technical knowledge. One focuses on knowledge-based innovations and the economic function of the university in terms of technology transfer, intellectual property, university-industry-government relations, etc. Faculties other than engineering or(More)
In 1998, the UK government introduced wealth creation as a “third mission” for universities in addition to teaching and research, and backed it with £50 million a year (Klein, 2002; Martin & Tang, 2007; Molas-Gallart et al., 2002). The idea of organizing a third mission—in addition to research and higher education—however, is much older, for example, in the(More)