Elzbieta Pityńska-Korab

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Leflunomide (LMF) is an immunemodulatory drug used in the therapy of Rheumatoid Arthritis (RA). After oral administration in the mucosa of digestive tract LMF is quickly converted to an active metabolite A77126 which is a competitive inhibitor of dihydroorotate dehydrogenase--enzyme required in pirymidyne synthesis resulting in decreased proliferation of T(More)
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