Elwira Gurdziel

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Although melatonin is approved only for the treatment of jet-lag syndrome and some types of insomnia, clinical data suggest that it is effective in the adjunctive therapy of osteoporosis, cataract, sepsis, neurodegenerative diseases, hypertension, and even cancer. Melatonin also modulates the electrical activity of neurons by reducing glutamatergic and(More)
1011 Review – The multidrug transporter P-glycoprotein in pharmacoresistance to antiepileptic drugs. 1038 Review – Role of the SOCS in monocytes/macro-phages-related pathologies. Are we getting closer to a new pharmacological target? Krzysztof 1055 Review – 11>-Hydroxysteroid dehydrogenase type 1: potential therapeutic target for metabolic syndrome. 1066(More)
BACKGROUND The aim of the study was to examine effects of an acute and chronic treatment with trazodone, a serotonin antagonist and reuptake inhibitor (SARI), on the protective activity of four classical antiepileptic drugs provided in the maximal electroshock test in mice. METHODS Electroconvulsions were produced in mice by means of an alternating(More)
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