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PURPOSE Somatostatin (SST) analogues have been used to treat proliferative diabetic retinopathy, pseudotumor cerebri, thyroid orbitopathy, and cystoid macular edema. There is a paucity of published data in regards to cell-specific distribution of SST receptors (SSTR) in normal human eye tissues. Gene expression for all five known SSTRs in normal human(More)
Drugs that block norepinephrine reuptake offer promise as opioid potentiators, because norepinephrine mediates opioid analgesia but not side effects such as sedation or nausea. In a two-by-two factorial design, we randomized 62 inpatients with pain following major surgery to receive either desipramine, 50 mg by mouth, or placebo at 6 a.m. on the first day(More)
PURPOSE To describe the course and outcome of treatment of advanced Acanthamoeba sclerokeratitis with intravenous pentamidine. METHODS A case of advanced Acanthamoeba sclerokeratitis was resistant to conventional therapy and was treated with intravenous pentamidine. The eye was later removed due to incapacitating pain. RESULTS The eye showed(More)
Sir, We present a rare case oferosion ofa duodenal ulcer into the liver in a gentleman with few risk factors for peptic ulcer disease (PUD) and on long term protium pump inhibitor (PPI). An 85 yearold male, who hadbeen on omeprazole for 18 months, was admitted with sub acute small bowel obstruction of 2 weeks duration. His past medical history was Type 2(More)
Demyelination involving both the peripheral and central nervous system, seen with Acute Severe Combined Demyelination, results in a combination of the deficits from Acute Inflammatory Demyelinating Polyneuropathy and Acute Disseminated Encephalomyelitis. The unique medical, physical, psychosocial and functional challenges this disorder presents to the(More)
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