Else Jacobsen

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Patients with cirrhosis of the liver often complain of tiredness and a lack of strength at physical exercise. Other investigators have found that muscle strength, work capacity, and maximal oxygen consumption are reduced in cirrhosis. We hypothesized that mitochondrial maximal rate of ATP synthesis in skeletal muscle may be impaired in these patients. This(More)
Acetazolamide, which reversibly inhibits carbonic anhydrase, is a useful diuretic in alkalotic and over-hydrated patients. In two earlier investigations we have consistently found increases in the arterial and venous oxygen saturation and tension when patients were treated with acetazolamide 15 mg·kg-1. A plausible explanation of this phenomenon is that(More)
INTRODUCTION This study evaluated health-related quality of life (HRQoL) in children and adolescents undergoing cosmetic surgery for pectus excavatum (PE) compared to a group of healthy children. METHODS The Intervention Group consisted of 172 children and adolescents undergoing surgery for PE between 2003 and 2005, aged 8-20 years; 86% were males. A(More)
Ergotamine was used to induce arterial contraction in vitro (measurement of isometric tension in segments from 3 human temporal arteries) and in vivo (peripheral systolic blood pressure measured by strain gauge plethysmography in 5 migrainous patients). In both these models of ergotism, the directly acting vasodilator nitroglycerine (NTG) effectively(More)
Esophageal peristalsis in the middle and distal esophagus was analyzed in nine healthy people before, during, and after food intake. A significant increase in amplitude of contractions occurred during and after eating. Furthermore, a significant increase in duration and propagation time of contractions occurred in the distal part of the esophagus during(More)
Eighty-nine patients, all below the age of 50 and under suspicion of dementia underwent computed tomography. The degree of cerebral atrophy was visually estimated and also calculated using different ventricular diameters and the mean width of four cortical sulci. The degree of dementia was evaluated by a neurological specialist. No correlation between(More)
It is not known how extensively a localised flexor tendon injury affects the entire tendon. This study examined the extent of and relationship between histopathologic and gene expression changes in equine superficial digital flexor tendon after a surgical injury. One forelimb tendon was hemi-transected in six horses, and in three other horses, one tendon(More)