Elrashid Saleh Mahdi

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BACKGROUND The purpose of this study was to select appropriate surfactants or blends of surfactants to study the ternary phase diagram behavior of newly introduced palm kernel oil esters. METHODS Nonionic surfactant blends of Tween(®) and Tween(®)/Span(®) series were screened based on their solubilization capacity with water for palm kernel oil esters.(More)
INTRODUCTION As a topical delivery system, a nanoscaled emulsion is considered a good carrier of several active ingredients that convey several side effects upon oral administration, such as nonsteroidal anti-inflammatory drugs (NSAIDs). OBJECTIVE We investigated the in vitro permeation properties and the in vivo pharmacodynamic activities of different(More)
The surface activity of some non-steroidal anti-inflammatory agents like ibuprofen was investigated extensively. This fact has attracted the researchers to extend this behavior to other agents like piroxicam. Piroxicam molecules are expected to orient at the interface of oil and aqueous phase. The aim of this study was, firstly, to assess the surface and(More)
BACKGROUND Recently there has been a remarkable surge of interest about natural products and their applications in the cosmetic industry. Topical delivery of antioxidants from natural sources is one of the approaches used to reverse signs of skin aging. The aim of this research was to develop a nanoemulsion cream for topical delivery of 30% ethanolic(More)
Micro-emulsions and sometimes nano-emulsions are well known candidates to deliver drugs locally. However, the poor rheological properties are marginally affecting their acceptance pharmaceutically. This work aimed to modify the poor flow properties of a nano-scaled emulsion comprising palm olein esters as the oil phase and ibuprofen as the active ingredient(More)
1. School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800 Minden, Pulau Penang, Malaysia. TEL: +60164849551; Email: muthana_albuldawy(at)yahoo.com 2. Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia. 3. Faculty of Science, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia(More)
1. School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800 Minden, Pulau Penang, Malaysia. TEL: +60164849551; Email: muthana_albuldawy(at)yahoo.com 2. Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia. 3. Faculty of Science, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia(More)
INTRODUCTION During recent years, there has been growing interest in use of topical vehicle systems to assist in drug permeation through the skin. Drugs of interest are usually those that are problematic when given orally, such as piroxicam, a highly effective anti-inflammatory, anti-pyretic, and analgesic, but with the adverse effect of causing(More)
2Department of Physiology, School of Pharmaceutical SciencesUniversiti Sains Malaysia, 11800 Minden, Penang, Malaysia. A b s t r a c t The purpose of this research was to study of physicochemical properties of the extracts and to develop and validate HPLC method in order to study their solubility in organic and aqueous vehicles and partition coefficients.(More)
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